Description

2-Amino-4-methyl-3-nitropyridine (CAS No. 6635-86-5) is a high-purity nitro-substituted pyridine derivative with the molecular formula C₆H₇N₃O₂. This compound, also known by its IUPAC name 4-methyl-3-nitropyridin-2-amine, is a versatile building block in organic synthesis and pharmaceutical research. It features a reactive amino group and a nitro group on a pyridine ring, making it valuable for heterocyclic chemistry applications. Our product is rigorously tested for purity (typically ≥97% by HPLC) and is supplied as a fine yellow crystalline powder with optimal stability under recommended storage conditions (2-8°C in airtight containers). Ideal for medicinal chemistry, agrochemical development, and material science research, this compound is packaged in amber glass vials with certified analytical data (NMR, MS, and HPLC reports available upon request).

Properties

• CAS Number: 6635-86-5
• Complexity: 156
• IUPAC Name: 4-methyl-3-nitro-pyridin-2-amine
• InChI: InChI=1S/C6H7N3O2/c1-4-2-3-8-6(7)5(4)9(10)11/h2-3H,1H3,(H2,7,8)
• InChI Key: IKMZGACFMXZAAT-UHFFFAOYSA-N
• Exact Mass: 153.053826475
• Molecular Formula: C6H7N3O2
• Molecular Weight: 153.14
• SMILES: CC1=C(C(=NC=C1)N)[N+](=O)[O-]
• Topological: 84.7
• Monoisotopic Mass: 153.053826475
• Synonyms: 2-Amino-4-methyl-3-nitropyridine, DTXSID80287771, DTXCID10238918, 626-702-2, 6635-86-5, 2-Amino-3-nitro-4-picoline, 4-methyl-3-nitropyridin-2-amine, 2-Pyridinamine, 4-methyl-3-nitro-, 4-methyl-3-nitro-pyridin-2-ylamine, MFCD00006315, CHEMBL3981727, 4-methyl-3-nitro-2-pyridylamine, 2-Amino-3-Nitro-4-Methylpyridine, 2-amino-4-methyl-3-nitro-pyridine, 4mrz, 2-amino-4-methyl-3-nitro pyridine, 2ZV, NSC52453, Cambridge id 5510884, SCHEMBL204345, SCHEMBL4053942, 2-amino-4-methyl-3nitropyridine, 4-methyl-3nitro-2-aminopyridine, 4-Methyl-3-nitropyridine-2-amine, BCP23369, CS-D1521, 4-Methyl-3-nitro-2-pyridinamine #, BDBM50532275, NSC 52453, NSC-52453, SBB006636, AKOS005145594, GS-6881, PB25894, Pyridine, 2-amino-3-nitro-4-methyl-, 2-Amino-4-methyl-3-nitropyridine, 98%, AC-24957, SY008383, DB-020438, DS-000780, A1888, ST50306966, EN300-36952, Q27453428, F0001-1767, Z380865216, 2-Amino-3-nitro-4-picoline (2-Amino-4-methyl-3-nitropyridine), InChI=1/C6H7N3O2/c1-4-2-3-8-6(7)5(4)9(10)11/h2-3H,1H3,(H2,7,8

Application

2-Amino-4-methyl-3-nitropyridine serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antimicrobial agents. Researchers utilize its nitro group for reduction reactions to form diamino derivatives, which are precursors for fused heterocyclic systems. The compound’s structural features make it valuable for studying structure-activity relationships in drug discovery programs targeting enzyme modulation.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.