Description

2-Amino-4-chloropyridine (CAS: 19798-80-2) is a high-purity heterocyclic organic compound with the molecular formula C₅H₅ClN₂. This fine chemical serves as a versatile building block in pharmaceutical synthesis, agrochemical development, and materials science research. The presence of both amino and chloro functional groups on the pyridine ring enables diverse reactivity, making it valuable for nucleophilic substitution reactions, metal-catalyzed cross-couplings, and as a precursor for more complex nitrogen-containing heterocycles. Our product is supplied as ≥97% pure crystalline solid with rigorous QC validation including HPLC, NMR, and mass spectrometry. Ideal for medicinal chemistry applications where precise structural modification is required. Available in research quantities from grams to multi-kilogram batches with custom purity and packaging options.

Properties

• CAS Number: 19798-80-2
• Complexity: 76.8
• IUPAC Name: 4-chloropyridin-2-amine
• InChI: InChI=1S/C5H5ClN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)
• InChI Key: RQMWVVBHJMUJNZ-UHFFFAOYSA-N
• Exact Mass: 128.0141259
• Molecular Formula: C5H5ClN2
• Molecular Weight: 128.56
• SMILES: C1=CN=C(C=C1Cl)N
• Topological: 38.9
• Monoisotopic Mass: 128.0141259
• Synonyms: 2-Amino-4-chloropyridine, 19798-80-2, 4-Chloro-2-pyridinamine, DTXSID70342444, DTXCID30293524, 629-610-0, 4-chloropyridin-2-amine, 4-Chloro-pyridin-2-ylamine, 2-Pyridinamine, 4-chloro-, MFCD04113820, 4-chloro-2-pyridylamine, 2-amino-4-chloro-pyridine, CHEMBL293728, 2-Amino-4-chloro pyridine, F1926-0004, Pyridines, 2-Amino4-chloropyridine, 2-amino-4-chloropyridin, 4-chloro pyridin-2-amine, 4-chloro-2-pyridinylamine, 4-chloropyridin-2-ylamine, 4-chloro-2-amino-pyridine, 2-Amino-4-chloropyrinidine, 4-Chloro-2-pyridinamine #, AF-399/42648911, SCHEMBL200134, SCHEMBL907780, pyridine, 2-amino-4-chloro-, SCHEMBL11547415, SCHEMBL15094430, SCHEMBL23890777, (4-chloro-pyridin-2-yl)-amine, 4-CHLORO-2-AMINOPYRIDINE, 2-Amino-4-chloropyridine, 97%, HMS1655J15, SMSSF-0044293, BCP27213, BBL011142, BDBM50091810, CL0032, SBB051892, STK802454, AKOS000320218, AC-2716, CCG-303312, CS-W008962, FA15644, PB32361, PS-5339, HY-60325, SY002647, DB-000134, A2152, ST45175164, EN300-64890, 4-Chloro-2-aminopyridine 4-Chloro-2-pyridinamine l (4-Chloropyridin-2-yl)amine

2-Amino-4-chloropyridine is widely employed as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antimicrobial agents. In material science, it serves as a precursor for functionalized pyridine derivatives used in coordination chemistry and ligand design. The compound’s reactive sites allow for selective modification, making it valuable for structure-activity relationship studies in drug discovery programs.

Safety and Hazards

GHS Hazard Statements

• H302 (93.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (97.9%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (97.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (95.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (93.6%)
• Skin Irrit. 2 (97.9%)
• Eye Irrit. 2 (97.9%)
• STOT SE 3 (95.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.