Description

2-Amino-4-bromopyridine (CAS No. 84249-14-9) is a high-purity brominated pyridine derivative widely used in pharmaceutical, agrochemical, and materials science research. With the molecular formula C₅H₅BrN₂, this compound serves as a versatile building block for organic synthesis, particularly in the preparation of heterocyclic compounds, ligands, and active pharmaceutical intermediates. Our product is rigorously tested to ensure ≥97% purity, making it ideal for demanding applications in medicinal chemistry and catalysis. Available in sealed packaging to maintain stability, it is supplied as a fine crystalline powder with excellent solubility in common organic solvents such as DMSO, ethanol, and dichloromethane. Store in a cool, dry place under inert conditions for optimal shelf life.

Properties

• CAS Number: 84249-14-9
• Complexity: 76.8
• IUPAC Name: 4-bromopyridin-2-amine
• InChI: InChI=1S/C5H5BrN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)
• InChI Key: BAQKUNMKVAPWGU-UHFFFAOYSA-N
• Exact Mass: 171.96361
• Molecular Formula: C5H5BrN2
• Molecular Weight: 173.01
• SMILES: C1=CN=C(C=C1Br)N
• Topological: 38.9
• Monoisotopic Mass: 171.96361
• Synonyms: 2-Amino-4-bromopyridine, 84249-14-9, DTXSID80351204, DTXCID80302271, 640-931-5, 4-bromopyridin-2-amine, MFCD01646115, 4-Bromo-2-pyridinamine, 4-Bromopyridin-2-ylamine, 4-bromanylpyridin-2-amine, 2-Pyridinamine, 4-bromo-, 4-bromo-2-pyridylamine, 4-bromo-pyridin-2-ylamine, HEW, 2-Amino-4-brompyridine, 4-bromopyridine-2-amine, 4-Bromo-2-amine-pyridine, 4-bromo-pyridin-2-yl-amine, SCHEMBL246592, 4-BROMO-2-AMINOPYRIDINE, SCHEMBL11544847, 2-Amino-4-bromopyridine, 97%, BAQKUNMKVAPWGU-UHFFFAOYSA-N, BCP24594, CS-D0698, AC-032, BBL100137, SBB016050, STL224003, AKOS000267487, FA09168, PB12936, PS-5241, HY-41000, SY005797, DB-006739, DB-009061, A2339, ST45175021, EN300-53481, A67308, AC-907/34116002, AC-907/34116003, F3099-7183, Z802558928

2-Amino-4-bromopyridine is a key intermediate in the synthesis of bioactive molecules, including kinase inhibitors and antimicrobial agents. It is employed in Suzuki-Miyaura cross-coupling reactions to construct complex pyridine-based scaffolds for drug discovery. Researchers also utilize it to develop luminescent materials and coordination complexes for catalytic applications. Its bromine moiety enables further functionalization via halogen-metal exchange or nucleophilic substitution.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (16%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (10%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (12%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (16%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (12%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.