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Atomfair 2-Amino-3-(trifluoromethyl)pyridine C6H5F3N2 CAS 183610-70-0

2-Amino-3-(trifluoromethyl)pyridine (CAS No. 183610-70-0) is a high-purity fluorinated pyridine derivative widely utilized in pharmaceutical research, agrochemical development, and advanced material synthesis. With the molecular formula C6H5F3N2, this compound features a reactive amino group adjacent to an electron-withdrawing trifluoromethyl substituent, making it a versatile intermediate for nucleophilic substitution, cross-coupling reactions, and heterocyclic scaffold construction. Our product is rigorously tested to ensure ≥97% purity (GC/HPLC) and is supplied as a crystalline solid with excellent shelf stability under recommended storage conditions (2-8°C, inert atmosphere). Ideal for medicinal chemistry applications requiring trifluoromethylated building blocks, this compound is available in research (100g) quantities with customizable…

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Description

2-Amino-3-(trifluoromethyl)pyridine (CAS No. 183610-70-0) is a high-purity fluorinated pyridine derivative widely utilized in pharmaceutical research, agrochemical development, and advanced material synthesis. With the molecular formula C6H5F3N2, this compound features a reactive amino group adjacent to an electron-withdrawing trifluoromethyl substituent, making it a versatile intermediate for nucleophilic substitution, cross-coupling reactions, and heterocyclic scaffold construction. Our product is rigorously tested to ensure ≥97% purity (GC/HPLC) and is supplied as a crystalline solid with excellent shelf stability under recommended storage conditions (2-8°C, inert atmosphere). Ideal for medicinal chemistry applications requiring trifluoromethylated building blocks, this compound is available in research (100g) quantities with customizable packaging options including amber glass vials and moisture-resistant containers.

Properties

  • CAS Number: 183610-70-0
  • Complexity: 134
  • IUPAC Name: 3-(trifluoromethyl)pyridin-2-amine
  • InChI: InChI=1S/C6H5F3N2/c7-6(8,9)4-2-1-3-11-5(4)10/h1-3H,(H2,10,11)
  • InChI Key: YWOWJQMFMXHLQD-UHFFFAOYSA-N
  • Exact Mass: 162.04048265
  • Molecular Formula: C6H5F3N2
  • Molecular Weight: 162.11
  • SMILES: C1=CC(=C(N=C1)N)C(F)(F)F
  • Topological: 38.9
  • Monoisotopic Mass: 162.04048265
  • Synonyms: 2-Amino-3-(trifluoromethyl)pyridine, 183610-70-0, DTXSID10375413, DTXCID30326442, 663-228-5, 3-(trifluoromethyl)pyridin-2-amine, 2-amino-3-trifluoromethylpyridine, 2-Pyridinamine, 3-(trifluoromethyl)-, 3-(Trifluoromethyl)-2-pyridinamine, MFCD04972538, 3-trifluoromethyl-pyridin-2-ylamine, EN300-117174, 3-(trifluoromethyl)-2-pyridylamine, SCHEMBL182868, SCHEMBL183159, SCHEMBL2067154, 2-amino-trifluoromethyl pyridine, SCHEMBL16445619, BDBM625990, RB1078, SBB051909, AKOS005064111, AB21173, AC-2718, CS-W010864, DS-0639, FS-1722, SY002651, 2-Amino-3-(trifluoromethyl)pyridine, 97%, DB-025287, DB-329855, ST50949493

2-Amino-3-(trifluoromethyl)pyridine serves as a key intermediate in the synthesis of trifluoromethyl-substituted pharmaceuticals, particularly kinase inhibitors and antiviral agents. The compound’s unique electronic properties facilitate its use in palladium-catalyzed cross-coupling reactions for constructing complex heterocycles. Researchers employ this building block to develop agrochemicals with enhanced metabolic stability due to the trifluoromethyl group’s lipophilicity. It also finds application in material science as a precursor for fluorinated liquid crystals and conductive polymers.

Safety and Hazards

GHS Hazard Statements

  • H301 (97.5%): Toxic if swallowed [Danger Acute toxicity, oral]
  • H317 (97.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P333+P317, P337+P317, P362+P364, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 3 (97.5%)
  • Skin Sens. 1 (97.5%)
  • Eye Irrit. 2A (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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