Description

(1R,2S)-(+)-cis-1-Amino-2-indanol (CAS: 136030-00-7) is a high-purity chiral compound with the molecular formula C₉H₁₁NO. This enantiomerically enriched amino alcohol is widely utilized in asymmetric synthesis, pharmaceutical research, and as a key intermediate in the preparation of bioactive molecules. Its rigid indane scaffold and cis-configuration make it an excellent ligand for chiral catalysts and resolving agents. Available at ≥99% purity, this product is rigorously tested for identity, potency, and impurities (HPLC, NMR) to ensure consistent performance in sensitive applications. Suitable for use under inert atmospheres and stored at 2-8°C to maintain stability.

Properties

• CAS Number: 136030-00-7
• Complexity: 148
• IUPAC Name: (1R,2S)-1-aminoindan-2-ol
• InChI: InChI=1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m0/s1
• InChI Key: LOPKSXMQWBYUOI-DTWKUNHWSA-N
• Exact Mass: 149.084063974
• Molecular Formula: C9H11NO
• Molecular Weight: 149.19
• SMILES: C1[C@@H]([C@@H](C2=CC=CC=C21)N)O
• Topological: 46.3
• Monoisotopic Mass: 149.084063974
• Synonyms: (1R,2S)-(+)-cis-1-Amino-2-indanol, cis-1-Amino-2,3-dihydro-1H-inden-2-ol, (+)-cis-1-amino-2-indanol, 603-940-5, 136030-00-7, (1R,2S)-1-amino-2-indanol, (1R,2S)-1-amino-2,3-dihydro-1H-inden-2-ol, cis-1-Amino-2-indanol, 7480-35-5, 140632-20-8, 1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1R,2S)-rel-, 13630-00-7, 1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1R,2S)-, (1R,2S)-(+)-1-Amino-2-indanol, Cis-1-Amino-2-hydroxyindan, 71S3J7NU1B, 7ZP212ZC8J, (1R,2S)-(+)-1-Amino-2-hydroxyindan, 1-Amino-2-indanol, cis-(+)-, 1-Amino-2-indanol, cis-(+/-)-, MFCD00216656, (1R,2S)-2,3-Dihydro-2-hydroxyinden-1-ylamine, (1r,2s)-(+)-cis-1-aminoindan-2-ol, (2S,1R)-1-aminoindan-2-ol, MFCD01318239, (1r,2s)-1-amino-2-hydroxyindane, (1r,2s)-cis-1-amino-2-indanol, cis 1-amino-2-indanol, cis-1 -amino-2-indanol, EC 422-660-2, UNII-71S3J7NU1B, UNII-7ZP212ZC8J, (1R,2S)-amino-2-indanol, SCHEMBL163842, Racemic cis-1-amino-2-indanol, CHEMBL4546964, 1-(R)-amino-2-(S)-indanol, (1R,2S)-1-Aminoindan-2-ol, cis-(+/-)-1-aminoindan-2-ol, (1R,2S)-1-amino-indan-2-ol, cis-(1r,2s)-1-amino-2-indanol, cis-(1R,2S)-l-amino-2-indanol, (1R, 2S)-1-amino-indan-2-ol, (1R,2S)-1-Amino-2-hydroxyindan, (1r, 2s)-cis-1-amino-2-indanol, SBB006600, AKOS005255542, AC-4656, CS-W007401, FA01885, HY-W007401, PS-4272, (1R, 2S)-(+)-1-amino-2-indanol, BP-10106, ST078862, (1r, 2s)-(+)-cis-1-amino-2-indanol, (1R,2S) -(+)-cis-1-amino-2-indanol, (1R,2S)-(-)-2-hydroxy-indan-1-ylamine, DB-351159, (1R,2S)-(+)-cis-1-Amino-2-hydroxyindane, EN300-53073, P15222, (1R,2S)-(+)-cis-1-Amino-2-indanol, 99%, rel-(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, 1H-Inden-2-ol,1-amino-2,3-dihydro-, (1R,2S)-rel-, Z784894996

(1R,2S)-(+)-cis-1-Amino-2-indanol serves as a versatile chiral auxiliary in asymmetric hydrogenations and organocatalysis. It is employed in the synthesis of HIV protease inhibitors like Indinavir and other pharmacologically active compounds. Researchers also utilize it to prepare chiral ligands for transition-metal catalysts in enantioselective transformations. Its applications extend to resolution of racemic acids and as a building block for peptidomimetics.

Safety and Hazards

GHS Hazard Statements

• H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
• H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P261, P264+P265, P272, P273, P280, P302+P352, P305+P354+P338, P317, P321, P333+P317, P362+P364, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

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