Description

Description

1,5-Difluoro-2,4-dinitrobenzene (CAS No. 327-92-4) is a high-purity aromatic compound with the molecular formula C₆H₂F₂N₂O₄, widely utilized in organic synthesis and pharmaceutical research. This yellow crystalline solid exhibits excellent reactivity due to the presence of electron-withdrawing nitro and fluoro groups, making it a valuable intermediate for nucleophilic substitution reactions. With a molecular weight of 204.09 g/mol, it is soluble in organic solvents such as acetone, DMSO, and ethanol but insoluble in water. Ideal for laboratory-scale derivatization, cross-coupling, and fluorination studies, this compound is rigorously tested for purity (typically ??98% by GC or HPLC) and is supplied in secure, light-resistant packaging to ensure stability. Store in a cool, dry place under inert conditions to maintain optimal shelf life.

Application

1,5-Difluoro-2,4-dinitrobenzene serves as a versatile building block in the synthesis of fluorinated aromatic compounds, particularly in pharmaceutical and agrochemical research. Its electron-deficient structure facilitates nucleophilic aromatic substitution (S_NAr) reactions, enabling the introduction of heteroatoms or functional groups. Researchers employ it in the development of dyes, sensors, and advanced materials due to its robust reactivity. Additionally, it is used as a derivatizing agent for analytical chemistry applications, enhancing detection sensitivity in chromatographic methods.

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