Description

1,2-Thiazetidine-1,1-dione (CAS No. 34817-61-3) is a specialized heterocyclic sulfone compound with the molecular formula C₂H₅NO₂S. Also known by its IUPAC name thiazetidine 1,1-dioxide, this high-purity chemical is ideal for advanced research applications in organic synthesis, medicinal chemistry, and materials science. The four-membered thiazetidine ring system, featuring a sulfone (S=O₂) moiety, offers unique reactivity for ring-opening reactions and serves as a valuable building block for sulfur-containing heterocycles. Supplied as a white to off-white crystalline solid with ≥95% purity (HPLC), this compound is rigorously tested for quality and stability. Store in a cool, dry place under inert atmosphere to maintain optimal shelf life. For research use only.

Properties

• CAS Number: 34817-61-3
• Complexity: 130
• IUPAC Name: thiazetidine 1,1-dioxide
• InChI: InChI=1S/C2H5NO2S/c4-6(5)2-1-3-6/h3H,1-2H2
• InChI Key: GNPXXOFTVXIOLF-UHFFFAOYSA-N
• Exact Mass: 107.00409958
• Molecular Formula: C2H5NO2S
• Molecular Weight: 107.13
• SMILES: C1CS(=O)(=O)N1
• Topological: 54.6
• Monoisotopic Mass: 107.00409958
• Synonyms: 1,2-thiazetidine-1,1-dione, 828-496-1, 1,2-thiazetidine 1,1-dioxide, 34817-61-3, 1lambda6,2-thiazetidine-1,1-dione, thiazetidine 1,1-dioxide, MFCD02258342, 1lambda~6~,2-Thiazetidine-1,1-dione, 2-Thiazetidine-1,1-dione, SCHEMBL7790096, [1,2]thiazetidine 1,1-dioxide, DTXSID40514030, GNPXXOFTVXIOLF-UHFFFAOYSA-N, 1lambda,2-thiazetidine-1,1-dione, AKOS026728356, AT12682, BS-12665, SY177368, CS-0343136, EN300-41338, AB01002785-01, Z415933552, XGS

Application

1,2-Thiazetidine-1,1-dione serves as a key intermediate in the synthesis of strained heterocyclic compounds for pharmaceutical development. Its reactive sulfone group enables participation in [2+2] cycloadditions and nucleophilic ring-opening reactions. Researchers utilize this scaffold to explore novel β-lactam analogs with potential antimicrobial activity. The compound also finds use in polymer chemistry as a monomer for sulfur-containing specialty materials.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.