Description

1,1,1,3,3,3-Hexafluoro-2-methoxy-propane (CAS: 13171-18-1) is a high-purity fluorinated ether compound with the molecular formula C₄H₄F₆O. This specialty chemical is widely recognized for its unique physicochemical properties, including low global warming potential (GWP) and excellent thermal stability, making it an ideal candidate for advanced applications in research and industrial settings. It is commonly referred to as hexafluoroisopropyl methyl ether or HFE-356mmz, among other synonyms.

Our product is manufactured under stringent quality control measures to ensure ≥98% purity, as verified by GC-MS and NMR analysis. It is supplied in amber glass bottles under inert gas to maintain stability and prevent degradation. Suitable for use as a solvent, refrigerant, or precursor in organic synthesis, this compound is particularly valuable in pharmaceutical research (e.g., as a sevoflurane impurity reference standard) and electronics manufacturing (e.g., precision cleaning).

Key Specifications:
– Molecular Weight: 182.06 g/mol
– Boiling Point: ~34-36°C
– Density: 1.32 g/cm³ at 25°C
– Refractive Index: 1.26 (20°C)
– Storage: 2-8°C in a ventilated, dry environment

Properties

• CAS Number: 13171-18-1
• Complexity: 110
• IUPAC Name: 1,1,1,3,3,3-hexafluoro-2-methoxy-propane
• InChI: InChI=1S/C4H4F6O/c1-11-2(3(5,6)7)4(8,9)10/h2H,1H3
• InChI Key: VNXYDFNVQBICRO-UHFFFAOYSA-N
• Exact Mass: 182.01663372
• Molecular Formula: C4H4F6O
• Molecular Weight: 182.06
• SMILES: COC(C(F)(F)F)C(F)(F)F
• Topological: 9.2
• Monoisotopic Mass: 182.01663372
• Synonyms: hexafluoroisopropyl methyl ether, 13171-18-1, 1,1,1,3,3,3-Hexafluoro-2-methoxypropane, Propane, 1,1,1,3,3,3-hexafluoro-2-methoxy-, N8YMW3PAU7, ISO-FLUROTHYL, HFE 356MMZ, 1,1,1,3,3,3-hexafluoro-2-methoxy-propane, DTXSID80157187, SEVOFLURANE IMPURITY B [EP IMPURITY], BIS(TRIFLUOROMETHYL)METHYL METHYL ETHER, 1-(TRIFLUOROMETHYL)-2,2,2-TRIFLUOROETHYL METHYL ETHER, METHYL 1-(TRIFLUOROMETHYL)-2,2,2-TRIFLUOROETHYL ETHER, SEVOFLURANE IMPURITY B (EP IMPURITY), DTXCID1079678, Propane, 1,1,1,3,3,3-hexafluoro-2-methoxy-(9CI), 603-501-8, Isoindoklon, methyl hexafluoroisopropyl ether, 1,1,1,3,3,3-Hexafluoroisopropyl methyl ether, Iso-indoklon, 27215-56-1, ETHER, METHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL, Hexafluoropropyl methyl ether, 0Sevoflurane Related Compound B; Sevoflurane Impurity B, BRN 2324008, Methyl 1,1,1,3,3,3-hexafluoroisopropyl ether, MFCD00221772, UNII-N8YMW3PAU7, HFE-356mmz1, Hexafluoroisopropylmethylether, (CF3)2CHOCH3, SCHEMBL588586, SCHEMBL588587, SCHEMBL4306595, CSRAEQGFOHAXAU-UHFFFAOYSA-N, XMBJHGRKOPHHSI-UHFFFAOYSA-N, AKOS006229620, FS-4291, FH105055, DB-042051, DB-308106, CS-0150671, H1524, D91043, Q60459040

1,1,1,3,3,3-Hexafluoro-2-methoxy-propane serves as a versatile fluorinated solvent for sensitive reactions requiring inert media, such as Grignard syntheses or lithium battery electrolyte formulations. In pharmaceuticals, it is employed as a reference standard for sevoflurane impurity analysis (EP/BP/USP compliance). Its low toxicity and high volatility also make it suitable for precision cleaning in semiconductor fabrication and aerospace component degreasing.

Safety and Hazards

GHS Hazard Statements

• H225 (66.7%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (33.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P264, P264+P265, P280, P302+P352, P303+P361+P353, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501

Hazard Classes and Categories

• Flam. Liq. 2 (66.7%)
• Skin Irrit. 2 (33.3%)
• Eye Irrit. 2 (33.3%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.