Description

1,1,1-Trifluoro-3-iodopropane (CAS No. 460-37-7) is a high-purity fluorinated organic compound with the molecular formula C₃H₄F₃I. This specialized chemical is widely utilized in synthetic organic chemistry, pharmaceutical research, and materials science due to its unique trifluoromethyl and iodo functional groups. The compound is supplied as a clear, colorless to pale yellow liquid with a characteristic odor, and it is rigorously tested for purity and stability to ensure optimal performance in demanding applications. Proper storage under inert conditions is recommended to maintain its integrity.

Researchers and scientists rely on 1,1,1-Trifluoro-3-iodopropane for its versatility as a building block in nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for fluorinated compounds. Its well-defined structure and reactivity make it an invaluable tool for advanced chemical synthesis. Each batch is accompanied by comprehensive analytical data, including GC/MS, NMR, and HPLC profiles, to guarantee consistency and traceability for your experiments.

Properties

• CAS Number: 460-37-7
• Complexity: 48.6
• IUPAC Name: 1,1,1-trifluoro-3-iodo-propane
• InChI: InChI=1S/C3H4F3I/c4-3(5,6)1-2-7/h1-2H2
• InChI Key: ULIYQAUQKZDZOX-UHFFFAOYSA-N
• Exact Mass: 223.93098
• Molecular Formula: C3H4F3I
• Molecular Weight: 223.96
• SMILES: C(CI)C(F)(F)F
• Monoisotopic Mass: 223.93098
• Synonyms: 460-37-7, 1,1,1-Trifluoro-3-iodopropane, DTXSID10963475, DTXCID301018025, 670-532-1, 1-Iodo-3,3,3-trifluoropropane, 3-iodo-1,1,1-trifluoropropane, 3,3,3-Trifluoropropyl Iodide, MFCD00038531, Propane, 1,1,1-trifluoro-3-iodo-, 71215-70-8, 1,1,1-trifluoro-3-iodo-propane, trifluoroiodopropane, SCHEMBL9984, 3,3,3-Trifluoropropyliodide, 3,3,3-trifluoropropyl iodid, 3,3,3-trifluoro-1-iodopropane, 1-iodo-3,3,3-trifluoro-propane, (3,3,3-trifluoro)-1-iodopropane, BCP08523, FD2005, AKOS005063359, CS-W002174, FT45224, 1,1,1-Trifluoro-3-iodopropane, 97%, 1-Iodo-3,3,3-trifluoropropane over Cu, AS-10244, SY030988, DB-001183, DB-051349, T2588, EN300-156159

Application

1,1,1-Trifluoro-3-iodopropane is commonly employed as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its reactivity enables efficient incorporation of trifluoromethyl groups into complex molecules, enhancing their metabolic stability and bioavailability. Additionally, this compound serves as a valuable precursor in the preparation of fluorinated polymers and specialty materials with unique thermal and chemical resistance properties. Researchers also utilize it in palladium-catalyzed cross-coupling reactions to construct carbon-carbon bonds in target molecules.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.