Description

1,1-Difluoropropan-2-one (CAS No. 431-05-0) is a high-purity fluorinated ketone with the molecular formula C₃H₄F₂O. This specialty chemical is characterized by its two fluorine atoms at the 1-position, enhancing its reactivity and utility in advanced synthetic applications. Ideal for researchers and scientists, our product is rigorously tested to ensure ≥98% purity (GC), making it suitable for precise organic synthesis, pharmaceutical intermediates, and material science research. Packaged under inert gas to maintain stability, this compound is available in quantities ranging from 1g to 1kg, with custom bulk options available upon request. Store in a cool, dry place away from light and moisture to preserve its integrity.

Properties

• CAS Number: 431-05-0
• Complexity: 59.8
• IUPAC Name: 1,1-difluoropropan-2-one
• InChI: InChI=1S/C3H4F2O/c1-2(6)3(4)5/h3H,1H3
• InChI Key: XHILZHAQBOLGFD-UHFFFAOYSA-N
• Exact Mass: 94.02302107
• Molecular Formula: C3H4F2O
• Molecular Weight: 94.06
• SMILES: CC(=O)C(F)F
• Topological: 17.1
• Monoisotopic Mass: 94.02302107
• Synonyms: 1,1-difluoropropan-2-one, 1,1-Difluoro-2-propanone, 688-420-6, 1,1-difluoroacetone, 431-05-0, MFCD02262166, 2-Propanone, 1,1-difluoro-, Difluorazeton, 1,1-Difluoro-propan-2-one, SCHEMBL805272, SCHEMBL9226591, SCHEMBL17474451, DTXSID30393018, AC1257, BBL039784, SBB021370, STK349316, AKOS000305789, DA-17544, SY013768, A6975, CS-0121252, ST45092268, EN300-92972

Application

1,1-Difluoropropan-2-one serves as a versatile building block in organic synthesis, particularly in the preparation of fluorinated pharmaceuticals and agrochemicals. Its reactive difluoromethyl ketone group enables nucleophilic additions and carbonyl-based transformations. Researchers also utilize it in the development of specialty polymers and advanced materials due to its fluorine-enhanced properties. Additionally, it finds use as a precursor in the synthesis of biologically active molecules and ligands for catalysis.

Safety and Hazards

GHS Hazard Statements

• H225 (40%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H226 (40%): Flammable liquid and vapor [Warning Flammable liquids]
• H315 (60%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (60%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (60%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 2 (40%)
• Flam. Liq. 3 (40%)
• Skin Irrit. 2 (60%)
• Eye Irrit. 2A (60%)
• STOT SE 3 (60%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.