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Atomfair 1-(Trifluoromethylthio)pyrrolidine-2,5-dione C5H4F3NO2S

Description 1-(Trifluoromethylthio)pyrrolidine-2,5-dione (CAS No. 183267-04-1) is a high-purity fluorinated organic compound with the molecular formula C5H4F3NO2S . This specialized chemical features a pyrrolidine-2,5-dione (succinimide) core functionalized with a trifluoromethylthio (-SCF3) group, making it a valuable building block for pharmaceutical and agrochemical research. The compound’s unique structure offers enhanced lipophilicity and metabolic stability, critical for drug discovery applications. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a white to off-white crystalline powder under inert packaging to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling chemistry, and as a precursor for bioactive molecules targeting CNS disorders…

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Description

Description

1-(Trifluoromethylthio)pyrrolidine-2,5-dione (CAS No. 183267-04-1) is a high-purity fluorinated organic compound with the molecular formula C5H4F3NO2S. This specialized chemical features a pyrrolidine-2,5-dione (succinimide) core functionalized with a trifluoromethylthio (-SCF3) group, making it a valuable building block for pharmaceutical and agrochemical research. The compound’s unique structure offers enhanced lipophilicity and metabolic stability, critical for drug discovery applications. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a white to off-white crystalline powder under inert packaging to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling chemistry, and as a precursor for bioactive molecules targeting CNS disorders and inflammation.

  • CAS No: 183267-04-1
  • Molecular Formula: C5H4F3NO2S
  • Molecular Weight: 199.15
  • Exact Mass: 198.99148403
  • Monoisotopic Mass: 198.99148403
  • IUPAC Name: 1-(trifluoromethylsulfanyl)pyrrolidine-2,5-dione
  • SMILES: C1CC(=O)N(C1=O)SC(F)(F)F
  • Synonyms: 183267-04-1, 1-(Trifluoromethylthio)pyrrolidine-2,5-dione, 1-(trifluoromethylsulfanyl)pyrrolidine-2,5-dione, 1-[(trifluoromethyl)sulfanyl]pyrrolidine-2,5-dione, 1-[(trifluoromethyl)thio]-2,5-Pyrrolidinedione

Application

1-(Trifluoromethylthio)pyrrolidine-2,5-dione serves as a versatile intermediate in medicinal chemistry, particularly for introducing the pharmacophoric -SCF3 moiety into lead compounds. Researchers utilize it in the synthesis of potential kinase inhibitors and GABAA receptor modulators due to its electron-withdrawing properties. The compound has shown promise in developing PET radiotracers for neurological imaging. Its compatibility with palladium-catalyzed coupling reactions makes it valuable for creating diversified compound libraries in drug discovery programs.

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