Description

Description

1-Fluorocyclopropane-1-carboxylic acid (CAS No. 137081-41-5) is a high-purity fluorinated cyclopropane derivative with the molecular formula C₄H₅FO₂. This specialized carboxylic acid features a fluorine atom at the 1-position of the cyclopropane ring, offering unique reactivity and steric properties for advanced synthetic applications. Our product is rigorously tested to ensure ??98% purity (HPLC/GC) and is supplied as a white to off-white crystalline solid with excellent batch-to-batch consistency. Ideal for pharmaceutical intermediates, agrochemical research, and materials science, this compound is packaged under inert gas in amber glass vials to ensure stability. Technical specifications include: molecular weight 104.08 g/mol, melting point 85-89??C, and storage recommendations of 2-8??C in a dry environment. MSDS and analytical certificates are available upon request.

Application

1-Fluorocyclopropane-1-carboxylic acid serves as a versatile building block in medicinal chemistry, particularly for the synthesis of fluorinated analogs of bioactive compounds. The strained cyclopropane ring enhances binding affinity in drug discovery, while the fluorine atom improves metabolic stability. Researchers utilize this compound in peptide modifications and as a precursor for fluorinated heterocycles. Its unique structure also finds applications in material science for creating fluorinated polymers with tailored properties.

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