Description

Description

1-Fluoro-3-(trifluoromethoxy)benzene (CAS No. 1077-01-6) is a high-purity fluorinated aromatic compound with the molecular formula C₇H₄F₄O. This specialty chemical is characterized by its unique trifluoromethoxy and fluoro substituents on the benzene ring, making it a valuable intermediate in organic synthesis and materials science. It is supplied as a clear, colorless to pale yellow liquid with exceptional stability under recommended storage conditions (2-8??C in a tightly sealed container). Ideal for researchers in pharmaceuticals, agrochemicals, and advanced materials, this compound is rigorously tested for purity (typically ??98% by GC) and consistency. Its structural features enable applications in nucleophilic substitution reactions, cross-coupling chemistry, and as a building block for liquid crystals or OLED materials. Available in quantities from grams to kilograms with optional certificates of analysis.

Application

1-Fluoro-3-(trifluoromethoxy)benzene serves as a key fluorinated building block in pharmaceutical research, particularly for developing CNS-active compounds where the trifluoromethoxy group enhances blood-brain barrier penetration. In materials science, it’s utilized to synthesize advanced polymers with enhanced thermal and chemical resistance. The compound also finds use in agrochemical production as a precursor for herbicides and pesticides with improved environmental stability.

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