Description
1-Ethoxy-1,1,2,2-tetrafluoroethane (CAS No. 512-51-6) is a high-purity fluorinated ether compound with the molecular formula C4H6F4O. This specialty chemical is characterized by its unique tetrafluoroethoxy structure, making it valuable for advanced applications in synthetic chemistry, pharmaceuticals, and materials science. It is supplied as a clear, colorless liquid with exceptional stability under standard conditions. Our product undergoes rigorous quality control to ensure >98% purity (GC), meeting the stringent requirements of research and industrial processes. Suitable for use as a solvent, intermediate, or reagent in organofluorine chemistry.
Key features:
- IUPAC Name: 1-ethoxy-1,1,2,2-tetrafluoroethane
- Molecular Weight: 146.08 g/mol
- Boiling Point: ~60-65°C (lit.)
- Density: ~1.25 g/cm3 at 25°C
- Storage: Maintain under inert atmosphere at 2-8°C
Properties
- CAS Number: 512-51-6
- Complexity: 82.6
- IUPAC Name: 1-ethoxy-1,1,2,2-tetrafluoro-ethane
- InChI: InChI=1S/C4H6F4O/c1-2-9-4(7,8)3(5)6/h3H,2H2,1H3
- InChI Key: HBRLMDFVVMYNFH-UHFFFAOYSA-N
- Exact Mass: 146.03547746
- Molecular Formula: C4H6F4O
- Molecular Weight: 146.08
- SMILES: CCOC(C(F)F)(F)F
- Topological: 9.2
- Monoisotopic Mass: 146.03547746
- Synonyms: 1-Ethoxy-1,1,2,2-tetrafluoroethane, 374pcE-beta-gamma, Ethane, 1-ethoxy-1,1,2,2-tetrafluoro-, Ether, ethyl 1,1,2,2-tetrafluoroethyl, DTXSID4075249, DTXCID3040982, 680-776-0, 512-51-6, Ethyl 1,1,2,2-tetrafluoroethyl ether, 1,1,2,2-tetrafluoroethyl ethyl ether, MFCD00069162, SCHEMBL658787, SCHEMBL1579024, SCHEMBL4243748, SCHEMBL11883055, 1,1,2,2-tetrafluoroethyl ether, LAIDESKHUQONBF-UHFFFAOYSA-N, Ethoxy-1,1,2,2-tetrafluoroethane, SBB086457, ethyl1,1,2,2-tetrafluoroethyl ether, AKOS005063427, ethyl-1,1,2,2-tetrafluoroethyl ether, 1,1,2,2-Tetrafluoroethyl ether, 97%, MS-20255, E1019, D90583, ethyl 1,1,2,2-tetrafluoroethyl ether/HFE-374E
Application
1-Ethoxy-1,1,2,2-tetrafluoroethane serves as a versatile building block in fluoroorganic synthesis, particularly for introducing tetrafluoroethoxy groups. It finds application as a specialty solvent for fluoropolymer processing and as an intermediate in pharmaceutical development where fluorine substitution is desired. The compound’s unique electronic properties make it valuable for dielectric fluid formulations and as a precursor for surface modification agents.
Safety and Hazards
GHS Hazard Statements
- H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (83.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501
Hazard Classes and Categories
- Flam. Liq. 2 (100%)
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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