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Atomfair 1-Bromo-3,5-bis(trifluoromethyl)benzene C8H3BrF6

Description 1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS No. 328-70-1) is a high-purity halogenated aromatic compound with the molecular formula C8H3BrF6. This specialized chemical features a benzene ring substituted with a bromine atom and two trifluoromethyl groups at the 1, 3, and 5 positions, respectively, offering unique reactivity for advanced synthetic applications. Its electron-deficient aromatic system makes it a valuable intermediate in organofluorine chemistry , pharmaceutical synthesis , and material science . Available in >98% purity (GC), this compound is supplied in rigorously tested batches with detailed analytical certificates (COA) to ensure consistency for sensitive research. Suitable for use in cross-coupling reactions (e.g., Suzuki, Stille),…

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Description

Description

1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS No. 328-70-1) is a high-purity halogenated aromatic compound with the molecular formula C8H3BrF6. This specialized chemical features a benzene ring substituted with a bromine atom and two trifluoromethyl groups at the 1, 3, and 5 positions, respectively, offering unique reactivity for advanced synthetic applications. Its electron-deficient aromatic system makes it a valuable intermediate in organofluorine chemistry, pharmaceutical synthesis, and material science. Available in >98% purity (GC), this compound is supplied in rigorously tested batches with detailed analytical certificates (COA) to ensure consistency for sensitive research. Suitable for use in cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic substitutions, and as a building block for liquid crystals or agrochemicals. Packaged under inert gas in amber glass vials to prevent degradation.

  • CAS No: 328-70-1
  • Molecular Formula: C8H3BrF6
  • Molecular Weight: 293.00
  • Exact Mass: 291.93223
  • Monoisotopic Mass: 291.93223
  • IUPAC Name: 1-bromo-3,5-bis(trifluoromethyl)benzene
  • SMILES: C1=C(C=C(C=C1C(F)(F)F)Br)C(F)(F)F
  • Synonyms: 328-70-1, 1-Bromo-3,5-bis(trifluoromethyl)benzene, Benzene, 1-bromo-3,5-bis(trifluoromethyl)-, 3,5-bis(trifluoromethyl)-1-bromobenzene, EINECS 206-334-5

Application

This compound serves as a key intermediate in the synthesis of fluorinated pharmaceuticals and bioactive molecules due to its enhanced metabolic stability. Widely used in palladium-catalyzed cross-coupling reactions to create complex aryl structures for drug discovery. The trifluoromethyl groups impart lipophilicity, making derivatives valuable in agrochemical development. Also employed in materials science for constructing electron-accepting moieties in organic electronics.

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