Description

1-Bromo-2-fluoroethane (CAS No. 762-49-2) is a highly versatile halogenated organic compound with the molecular formula C₂H₄BrF. This colorless to pale yellow liquid is widely used in synthetic organic chemistry and pharmaceutical research due to its reactive bromo and fluoro functional groups. With a purity grade suitable for laboratory and industrial applications, our product is rigorously tested to ensure consistency and reliability. Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a building block for more complex fluorinated compounds. Packaged under inert gas to maintain stability and shipped with detailed technical data, including MSDS, NMR, and GC analysis reports.

Properties

• CAS Number: 762-49-2
• Complexity: 10
• IUPAC Name: 1-bromo-2-fluoro-ethane
• InChI: InChI=1S/C2H4BrF/c3-1-2-4/h1-2H2
• InChI Key: JTLAIKFGRHDNQM-UHFFFAOYSA-N
• Exact Mass: 125.94804
• Molecular Formula: C2H4BrF
• Molecular Weight: 126.96
• SMILES: C(CBr)F
• Monoisotopic Mass: 125.94804
• Physical Description: Pale yellow liquid;
• Boiling Point: 71-72 °C at 760 mm Hg
• Solubility: Soluble in alcohol, ether
• Density: 1.7044 at 25 °C/4 °C
• Refractive Index: Index of refraction: 1.4236 at 20 °C/D
• Synonyms: 1-BROMO-2-FLUOROETHANE, 762-49-2, 2-Fluoroethyl bromide, Ethane, 1-bromo-2-fluoro-, 2-Bromofluoroethane, 1-Fluoro-2-bromoethane, HSDB 6788, EINECS 212-100-3, 9B15FC1III, NSC-172603, DTXSID6073233, 2-FLUOROETHYL BROMIDE [HSDB], NSC 172603, 2Bromofluoroethane, 2Fluoroethyl bromide, Ethane, 1bromo2fluoro, DTXCID2047858, 212-100-3, 1-bromo-2-fluoro-ethane, UNII-9B15FC1III, 2-fluoroethylbromide, CH2FCH2Br, 2-bromo-1-fluoroethane, 1-bromo-2-flouro ethane, 1-bromo-2-fluoro ethane, 2-fluoro-1-bromo ethane, 2-fluoro-1-bromo-ethane, SCHEMBL29028, 1-bromanyl-2-fluoranyl-ethane, SCHEMBL6310195, SCHEMBL7977882, SCHEMBL14127161, JTLAIKFGRHDNQM-UHFFFAOYSA-, MFCD00039285, NSC172603, AKOS006228963, BS-12654, DB-005084, NS00042041, InChI=1/C2H4BrF/c3-1-2-4/h1-2H2, A838655, A901306, Q27272288

Application

1-Bromo-2-fluoroethane is commonly employed as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. It serves as a precursor for the introduction of fluoroethyl groups into target molecules, enhancing their biological activity. Researchers also utilize this compound in material science for modifying polymer properties and in radiochemistry for labeling applications. Its dual functionality makes it valuable in cross-coupling reactions and as a reagent in organofluorine chemistry.

Safety and Hazards

GHS Hazard Statements

• H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H300+H310 (100%): Fatal if swallowed or in contact with skin [Danger Acute toxicity, oral; acute toxicity, dermal]
• H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]
• H310 (100%): Fatal in contact with skin [Danger Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H420 (100%): Harms public health and the environment by destroying ozone in the upper atmosphere [Warning Hazardous to the ozone layer]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, P501, and P502

Hazard Classes and Categories

• Flam. Liq. 2 (100%)
• Acute Tox. 2 (100%)
• Acute Tox. 1 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (100%)
• Ozone 1 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.