Atomfair

Awaiting product image

Atomfair 1-Bromo-2-chloro-4-fluoro-5-nitrobenzene C6H2BrClFNO2 CAS 111010-08-3

1-Bromo-2-chloro-4-fluoro-5-nitrobenzene (CAS No. 111010-08-3) is a high-purity halogenated nitrobenzene derivative with the molecular formula C6H2BrClFNO2. This compound is a versatile intermediate in organic synthesis, featuring a unique combination of bromo, chloro, fluoro, and nitro substituents on a benzene ring, enabling precise regioselective modifications. Its crystalline solid form and well-defined structure (IUPAC name: 1-bromo-2-chloro-4-fluoro-5-nitrobenzene ) make it ideal for pharmaceutical, agrochemical, and materials science research. Packaged under inert conditions to ensure stability, this product is characterized by GC/HPLC and NMR to guarantee >98% purity. Suitable for Suzuki couplings, nucleophilic aromatic substitutions, and other advanced transformations. Handle with care under controlled conditions…

Category:

Description

1-Bromo-2-chloro-4-fluoro-5-nitrobenzene (CAS No. 111010-08-3) is a high-purity halogenated nitrobenzene derivative with the molecular formula C6H2BrClFNO2. This compound is a versatile intermediate in organic synthesis, featuring a unique combination of bromo, chloro, fluoro, and nitro substituents on a benzene ring, enabling precise regioselective modifications. Its crystalline solid form and well-defined structure (IUPAC name: 1-bromo-2-chloro-4-fluoro-5-nitrobenzene) make it ideal for pharmaceutical, agrochemical, and materials science research. Packaged under inert conditions to ensure stability, this product is characterized by GC/HPLC and NMR to guarantee >98% purity. Suitable for Suzuki couplings, nucleophilic aromatic substitutions, and other advanced transformations. Handle with care under controlled conditions due to potential reactivity.

Properties

  • CAS Number: 111010-08-3
  • Complexity: 189
  • IUPAC Name: 1-bromo-2-chloro-4-fluoro-5-nitro-benzene
  • InChI: InChI=1S/C6H2BrClFNO2/c7-3-1-6(10(11)12)5(9)2-4(3)8/h1-2H
  • InChI Key: YVDJBLFLBBBGMD-UHFFFAOYSA-N
  • Exact Mass: 252.89415
  • Molecular Formula: C6H2BrClFNO2
  • Molecular Weight: 254.44
  • SMILES: C1=C(C(=CC(=C1Br)Cl)F)[N+](=O)[O-]
  • Topological: 45.8
  • Monoisotopic Mass: 252.89415
  • Synonyms: 1-Bromo-2-chloro-4-fluoro-5-nitrobenzene, 111010-08-3, DTXSID60553789, DTXCID40504572, 867-705-0, Benzene, 1-bromo-2-chloro-4-fluoro-5-nitro-, MFCD20528320, 5-bromo-4-chloro-2-fluoronitrobenzene, SCHEMBL7872533, YVDJBLFLBBBGMD-UHFFFAOYSA-N, LEA01008, AKOS027273515, FD10713, AS-48879, SY244579, DB-250339, CS-0088553, EN300-4314051

Application

1-Bromo-2-chloro-4-fluoro-5-nitrobenzene is widely used as a key building block in the synthesis of complex aromatic compounds, particularly in pharmaceutical development for creating fluorinated drug candidates. Its multi-halogenated structure facilitates selective cross-coupling reactions in agrochemical research for novel pesticides and herbicides. The nitro group also serves as a precursor for amino or other functional groups via reduction, expanding its utility in materials science for advanced polymers or dyes.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products