Description

Description

1-Bromo-2-(bromomethyl)-4-fluorobenzene (CAS No. 112399-50-5) is a highly reactive brominated and fluorinated aromatic compound with the molecular formula C₇H₅Br₂F. This organohalide is a versatile intermediate in synthetic organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty materials. Its structure features both a bromine substituent and a reactive bromomethyl group on a fluorinated benzene ring, making it an excellent candidate for nucleophilic substitution, cross-coupling reactions, and further functionalization.

This compound is supplied as a high-purity solid or liquid (depending on storage conditions) and should be handled under inert conditions due to its sensitivity to moisture and air. It is ideal for researchers developing novel fluorinated compounds or exploring halogenated building blocks for drug discovery. Store in a cool, dry place away from light and oxidizing agents.

Application

1-Bromo-2-(bromomethyl)-4-fluorobenzene is widely used as a key intermediate in the synthesis of fluorinated aromatic compounds, particularly in pharmaceutical and agrochemical research. It serves as a precursor for Suzuki-Miyaura and other cross-coupling reactions to introduce fluorinated benzyl motifs into complex molecules. Researchers also utilize it in the development of liquid crystals, OLED materials, and other advanced functional materials requiring halogenated aromatic cores.

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