Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1,2,3,6-tetrahydropyridine C18H26BNO2 CAS 1048976-83-5

1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine (CAS: 1048976-83-5) is a high-purity boronic ester derivative with the molecular formula C18H26BNO2. This compound is a valuable synthetic intermediate, widely used in Suzuki-Miyaura cross-coupling reactions due to its stable pinacol boronate group. The benzyl-substituted tetrahydropyridine core enhances its reactivity in transition-metal-catalyzed transformations, making it ideal for constructing complex heterocyclic scaffolds in pharmaceutical and agrochemical research. Supplied as a crystalline solid, it is rigorously tested for purity (typically ≥95% by HPLC) and stored under inert conditions to ensure stability. Suitable for use in organic synthesis, medicinal chemistry, and material science applications.

Category:

Description

1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine (CAS: 1048976-83-5) is a high-purity boronic ester derivative with the molecular formula C18H26BNO2. This compound is a valuable synthetic intermediate, widely used in Suzuki-Miyaura cross-coupling reactions due to its stable pinacol boronate group. The benzyl-substituted tetrahydropyridine core enhances its reactivity in transition-metal-catalyzed transformations, making it ideal for constructing complex heterocyclic scaffolds in pharmaceutical and agrochemical research. Supplied as a crystalline solid, it is rigorously tested for purity (typically ≥95% by HPLC) and stored under inert conditions to ensure stability. Suitable for use in organic synthesis, medicinal chemistry, and material science applications.

Properties

  • CAS Number: 1048976-83-5
  • Complexity: 411
  • IUPAC Name: 1-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine
  • InChI: InChI=1S/C18H26BNO2/c1-17(2)18(3,4)22-19(21-17)16-10-12-20(13-11-16)14-15-8-6-5-7-9-15/h5-10H,11-14H2,1-4H3
  • InChI Key: SBZWAVVCJBBNSM-UHFFFAOYSA-N
  • Exact Mass: 299.2056592
  • Molecular Formula: C18H26BNO2
  • Molecular Weight: 299.2
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CCN(CC2)CC3=CC=CC=C3
  • Topological: 21.7
  • Monoisotopic Mass: 299.2056592
  • Synonyms: 1048976-83-5, 1-BENZYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1,2,3,6-TETRAHYDROPYRIDINE, 1-Benzyl-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester, MFCD11501654, 1-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine, SCHEMBL9952926, DTXSID80678049, SBZWAVVCJBBNSM-UHFFFAOYSA-N, (1-BENZYL-1,2,3,6-TETRAHYDROPYRIDIN-4-YL)BORONIC ACID PINACOL ESTER, AKOS015949248, CS-W001285, SB30375, 1,2,3,6-Tetrahydro-1-(phenylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, DS-13192, SY031554, DB-059223, 1-Benzyl-1,2,3,6-tetrahydropyridine-4-boronic acid, pinacol ester, 1-Benzyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,2,3,6-tetrahydro-pyridine, 1-Benzyl-4-(4 pound not4 pound not5 pound not5-tetramethyl-1 pound not3 pound not2-dioxaborolan-2-yl)-1 pound not2 pound not3 pound not6-tetrahydropyridine

Application

This compound is primarily employed as a key intermediate in palladium-catalyzed cross-coupling reactions, enabling the synthesis of biaryl and heteroaryl structures. Researchers utilize it in the development of pharmaceutical candidates, particularly for CNS-targeting molecules due to its benzyl-tetrahydropyridine moiety. It also serves as a precursor for boronic acid derivatives in sensor and polymer chemistry.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products