Description

1-Benzyl-2-chlorobenzimidazole (CAS No. 43181-78-8) is a high-purity benzimidazole derivative with the molecular formula C₁₄H₁₁ClN₂. This compound is a versatile heterocyclic building block widely used in pharmaceutical research, organic synthesis, and material science applications. The benzyl and chloro substituents on the benzimidazole core impart unique reactivity, making it valuable for nucleophilic substitution reactions and as a precursor for further functionalization.

Our product is synthesized under strict quality control, ensuring ≥95% purity (HPLC) with full characterization by ¹H NMR, ¹³C NMR, and mass spectrometry. Supplied as a white to off-white crystalline powder, it is packaged under inert atmosphere to guarantee stability. Ideal for medicinal chemistry applications, this compound shows particular promise in the development of kinase inhibitors and antimicrobial agents.

Key Specifications:
– Molecular Weight: 242.70 g/mol
– Melting Point: 128-132°C
– Storage: 2-8°C under nitrogen
– Hazard Codes: Xi (Irritant)

Properties

• CAS Number: 43181-78-8
• Complexity: 253
• IUPAC Name: 1-benzyl-2-chloro-benzimidazole
• InChI: InChI=1S/C14H11ClN2/c15-14-16-12-8-4-5-9-13(12)17(14)10-11-6-2-1-3-7-11/h1-9H,10H2
• InChI Key: PVLIRTAXXPPHCJ-UHFFFAOYSA-N
• Exact Mass: 242.0610761
• Molecular Formula: C14H11ClN2
• Molecular Weight: 242.70
• SMILES: C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2Cl
• Topological: 17.8
• Monoisotopic Mass: 242.0610761
• Synonyms: 43181-78-8, 1-benzyl-2-chlorobenzimidazole, DTXSID30396882, DTXCID60347741, 1-Benzyl-2-chloro-1H-benzo[d]imidazole, 2-Chloro-1-(phenylmethyl)-benzimidazole, 1-benzyl-2-chloro-1H-benzimidazole, 1-Benzyl-2-chloro-1H-benzoimidazole, 1-benzyl-2-chloro-1H-1,3-benzodiazole, N-benzyl-2-chlorobenzimidazole, 2-chloro-1-benzylbenzimidazole, SCHEMBL1169953, PVLIRTAXXPPHCJ-UHFFFAOYSA-N, STK395316, AKOS005442030, WS-01257, DB-311807, CS-0197230, ST50862667, W18755, AE-848/32321051

Application

1-Benzyl-2-chlorobenzimidazole serves as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research targeting kinase inhibition pathways. The chloro group at the 2-position allows for facile nucleophilic displacement reactions to create diverse benzimidazole derivatives. Researchers utilize this compound in the development of potential therapeutic agents for inflammatory diseases and cancer treatment. Its structural features make it valuable for studying structure-activity relationships in medicinal chemistry programs.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.