Description

1-(4-Aminophenyl)piperazine (CAS No. 67455-41-8) is a high-purity organic compound with the molecular formula C₁₀H₁₅N₃ and IUPAC name 4-piperazin-1-ylaniline. This aromatic amine derivative features a piperazine ring linked to an aniline moiety, making it a versatile intermediate for pharmaceutical synthesis, chemical research, and material science applications. Our product is rigorously tested for purity, stability, and consistency, ensuring reliable performance in sensitive reactions. Suitable for use in medicinal chemistry, ligand design, and heterocyclic compound synthesis, it is available in various packaging options to meet laboratory and industrial-scale demands. Store in a cool, dry place under inert conditions to maintain optimal quality.

Properties

• CAS Number: 67455-41-8
• Complexity: 146
• IUPAC Name: 4-piperazin-1-ylaniline
• InChI: InChI=1S/C10H15N3/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8,11H2
• InChI Key: VAVOYRCCWLRTMS-UHFFFAOYSA-N
• Exact Mass: 177.126597491
• Molecular Formula: C10H15N3
• Molecular Weight: 177.25
• SMILES: C1CN(CCN1)C2=CC=C(C=C2)N
• Topological: 41.3
• Monoisotopic Mass: 177.126597491
• Synonyms: 67455-41-8, 1-(4-Aminophenyl)piperazine, DTXSID60329709, DTXCID20280807, 624-685-6, 4-(Piperazin-1-yl)aniline, 4-piperazin-1-ylaniline, Benzenamine,4-(1-piperazinyl)-, 4-Piperazin-1-yl-phenylamine, 4-(1-piperazinyl)aniline, 1-(4-Amino-phenyl)-piperazine, 4-Piperazinoaniline, 4-piperazinylphenylamine, MFCD01365906, ChemDiv3_014096, 1-(p-Aminophenyl)piperazine, Oprea1_209661, Oprea1_539427, SCHEMBL531923, (4-piperazin-1-ylphenyl)amine, SCHEMBL2232832, CHEMBL2335385, SCHEMBL13724185, VAVOYRCCWLRTMS-UHFFFAOYSA-N, HMS1513A16, 4-(4-AMINOPHENYL)PIPERAZINE, 1-(4-Aminophenyl)piperazine, 97%, SBB010619, AKOS000301173, AB09097, IDI1_029894, TS-02468, ST50243160, EN300-142996, A835755

Application

1-(4-Aminophenyl)piperazine serves as a key building block in the synthesis of bioactive molecules, particularly in the development of CNS-targeting pharmaceuticals. It is utilized in the preparation of serotonin receptor ligands and dopamine modulators for neurological research. The compound also finds use in polymer chemistry as a crosslinking agent or functional monomer. Researchers employ it in the design of fluorescent probes and metal-chelating complexes.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Dam. 1 (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.