Description
Perfluoro-2-butyltetrahydrofuran (CAS No. 335-36-4) is a high-performance fluorinated solvent with the molecular formula C8F16O. This fully fluorinated cyclic ether is characterized by its exceptional chemical inertness, thermal stability, and low surface tension, making it ideal for demanding applications in research and industrial processes. Its unique perfluorinated structure ensures compatibility with reactive chemicals and high-temperature environments.
This solvent is widely recognized for its dielectric properties, non-flammability, and biocompatibility, which are critical in electronics, aerospace, and medical device testing. Available in various packaging options, our Perfluoro-2-butyltetrahydrofuran meets stringent quality standards for laboratory and industrial use. The product is supplied with comprehensive technical documentation, including SDS and analytical certificates.
Key features include ultra-low residue formation, excellent heat transfer characteristics, and resistance to oxidation. It is commonly used as a heat transfer fluid, dielectric coolant, or reaction medium in specialized synthetic applications. Due to its inert nature, it is also suitable for use as a reference standard in analytical chemistry.
Properties
- CAS Number: 335-36-4
- Complexity: 545
- IUPAC Name: 2,2,3,3,4,4,5-heptafluoro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)tetrahydrofuran
- InChI: InChI=1S/C8F16O/c9-1(10,4(15,16)7(20,21)22)2(11,12)6(19)3(13,14)5(17,18)8(23,24)25-6
- InChI Key: FYJQJMIEZVMYSD-UHFFFAOYSA-N
- Exact Mass: 415.9693652
- Molecular Formula: C8F16O
- Molecular Weight: 416.06
- SMILES: C1(C(C(OC1(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)F)(F)F)(F)F)(F)F
- Topological: 9.2
- Monoisotopic Mass: 415.9693652
- Physical Description: Liquid
- Synonyms: Perfluoro-2-butyltetrahydrofuran, 335-36-4, Fluorinert FC 75, 2,2,3,3,4,4,5-heptafluoro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)oxolane, MSL8VN7XHA, Furan, 2,2,3,3,4,4,5-heptafluorotetrahydro-5-(nonafluorobutyl)-, 2,2,3,3,4,4,5-Heptafluorotetrahydro-5-(nonafluorobutyl)furan, 2,2,3,3,4,4,5-heptafluoro-5-(nonafluorobutyl)tetrahydrofuran, CHEBI:39023, DTXSID60871632, FC-75, RM101, 2,2,3,3,4,4,5-HEPTAFLUOROTETRAHYDRO-5-(1,1,2,2,3,3,4,4,4-NONAFLUOROBUTYL)FURAN, Furan, 2,2,3,3,4,4,5-heptafluorotetrahydro-5-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-, Perfluoro(2nbutyltetrahydrofuran), DTXCID70819282, Heptafluorotetrahydro2(nonafluorobutyl)furan, Furan, heptafluorotetrahydro2(nonafluorobutyl), 2,2,3,3,4,4,5Heptafluorotetrahydro5(nonafluorobutyl)furan, Furan, 2,2,3,3,4,4,5heptafluorotetrahydro5(nonafluorobutyl), Furan, 2,2,3,3,4,4,5heptafluorotetrahydro5(1,1,2,2,3,3,4,4,4nonafluorobutyl), 206-389-5, Heptafluorotetrahydro(nonafluorobutyl)furan, 40464-54-8, Perfluoro(2-butyltetrahydrofuran), spectrasynq pfbthf, 11072-16-5, FC 75, MFCD00014513, FC75, Heptafluorotetrahydro-2-(nonafluorobutyl)furan, Furan, heptafluorotetrahydro(nonafluorobutyl)-, Furan, heptafluorotetrahydro-2-(nonafluorobutyl)-, fluorinert fc-75, perfluoro-compound fc-75, Fluorocarbon 77, EINECS 206-389-5, EINECS 254-933-5, fluorinert(r) fc-75, UNII-MSL8VN7XHA, 2-Nonafluorobutyl-heptafluorotetrahydrofuran, SCHEMBL63047, fluorinert(tm) (fc-75)(r), fluorinert ™ (fc-75) (reg), perfluoro-2-n-butyltetrahydrofurane, exadecafluoro-2-butyltetrahydrofuran, perfluoro(2-n-butyltetrahydrofuran), AKOS005063731, FP60439, NS00011165, NS00112221, D92031, perfluoro-2-butyltetrahydrofuran fc-75 mixture, Perfluoro-2-butyltetrahydrofuran, mixture of isomers, Q5424695, Perfluoro-2-n-butyltetrahydrofurane (mixture of isomers)
Perfluoro-2-butyltetrahydrofuran is extensively used as a heat transfer fluid in high-performance cooling systems due to its thermal stability and non-conductive properties. In electronics manufacturing, it serves as a dielectric testing medium for components requiring inert environments. The compound’s biocompatibility also makes it valuable in medical device testing and as a blood substitute in experimental oxygen transport studies.
Safety and Hazards
GHS Hazard Statements
- H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
- H413 (50%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statements
- P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (50%)
- Eye Irrit. 2 (50%)
- STOT SE 3 (50%)
- Aquatic Chronic 4 (50%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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