Description
2-(6-Bromopyridin-2-yl)ethanol (CAS No. 955370-07-7) is a high-purity brominated pyridine derivative with the molecular formula C7H8BrNO. This compound features a reactive bromine atom at the 6-position of the pyridine ring and a hydroxymethyl group at the 2-position, making it a versatile intermediate for pharmaceutical, agrochemical, and materials science research. Its IUPAC name is 2-(6-bromopyridin-2-yl)ethanol, and it is also known by synonyms such as 2-Bromo-6-(2-hydroxyethyl)pyridine and MFCD10000073. This product is rigorously tested for quality and consistency, ensuring optimal performance in synthetic applications. Available in various quantities, it is ideal for researchers requiring a reliable building block for cross-coupling reactions, ligand synthesis, or functional group transformations.
Properties
- CAS Number: 955370-07-7
- Complexity: 99.6
- IUPAC Name: 2-(6-bromo-2-pyridyl)ethanol
- InChI: InChI=1S/C7H8BrNO/c8-7-3-1-2-6(9-7)4-5-10/h1-3,10H,4-5H2
- InChI Key: BUSVXLMCEYFMCS-UHFFFAOYSA-N
- Exact Mass: 200.97893
- Molecular Formula: C7H8BrNO
- Molecular Weight: 202.05
- SMILES: C1=CC(=NC(=C1)Br)CCO
- Topological: 33.1
- Monoisotopic Mass: 200.97893
- Synonyms: 2-(6-bromopyridin-2-yl)ethanol, 955370-07-7, 2-Bromo-6-(2-hydroxyethyl)pyridine, MFCD10000073, 2-(6-BROMOPYRIDIN-2-YL)ETHAN-1-OL, SCHEMBL1020532, DTXSID90676536, BUSVXLMCEYFMCS-UHFFFAOYSA-N, AC1439, AKOS015856375, CS-W007189, DS-15404, SY037350, DB-080297, EN300-1913232
Application
2-(6-Bromopyridin-2-yl)ethanol is widely used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its bromine moiety enables participation in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions, while the hydroxyl group allows for further derivatization. This compound is also employed in agrochemical research for constructing pyridine-based herbicides and fungicides. Additionally, it serves as a precursor for ligands in catalysis and functional materials.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2A (100%)
- STOT SE 3 (100%)
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