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Atomfair 2-Amino-4-fluoropyridine C5H5FN2 CAS 944401-77-8

2-Amino-4-fluoropyridine (CAS No. 944401-77-8) is a high-purity fluorinated pyridine derivative with the molecular formula C5H5FN2. This compound, also known by its IUPAC name 4-fluoropyridin-2-amine , is a versatile building block in pharmaceutical and agrochemical synthesis. Its unique structure, featuring both an amino group and a fluorine substituent on the pyridine ring, makes it valuable for nucleophilic substitution reactions and as a precursor for heterocyclic compounds. Available in >98% purity (HPLC), this product is rigorously tested for consistency and stability, packaged under inert gas to ensure long shelf life. Ideal for medicinal chemistry, material science, and catalysis research.

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Description

2-Amino-4-fluoropyridine (CAS No. 944401-77-8) is a high-purity fluorinated pyridine derivative with the molecular formula C5H5FN2. This compound, also known by its IUPAC name 4-fluoropyridin-2-amine, is a versatile building block in pharmaceutical and agrochemical synthesis. Its unique structure, featuring both an amino group and a fluorine substituent on the pyridine ring, makes it valuable for nucleophilic substitution reactions and as a precursor for heterocyclic compounds. Available in >98% purity (HPLC), this product is rigorously tested for consistency and stability, packaged under inert gas to ensure long shelf life. Ideal for medicinal chemistry, material science, and catalysis research.

Properties

  • CAS Number: 944401-77-8
  • Complexity: 76.8
  • IUPAC Name: 4-fluoropyridin-2-amine
  • InChI: InChI=1S/C5H5FN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)
  • InChI Key: WCCFLOQQACDOAX-UHFFFAOYSA-N
  • Exact Mass: 112.04367633
  • Molecular Formula: C5H5FN2
  • Molecular Weight: 112.10
  • SMILES: C1=CN=C(C=C1F)N
  • Topological: 38.9
  • Monoisotopic Mass: 112.04367633
  • Synonyms: 2-Amino-4-fluoropyridine, 815-037-5, 944401-77-8, 4-fluoropyridin-2-amine, MFCD09260906, 4-FLUORO-2-PYRIDINAMINE, 4-fluoro-2-pyridylamine, 4-FLUORO-PYRIDIN-2-YLAMINE, Amino-4-fluoropyridine, 4-fluoro-pyridin-2-amine, SCHEMBL310167, SCHEMBL4187324, SCHEMBL11555243, SCHEMBL15094216, SCHEMBL23104502, DTXSID20592836, WCCFLOQQACDOAX-UHFFFAOYSA-N, BCP26403, BBL101541, SBB051908, STL555337, 2-amino-4-fluoropyridine, AldrichCPR, AKOS006238128, AB50025, AC-3168, CS-W005118, FA10596, HY-W005118, SY004151, TS-01558, DB-082075, A2976, EN300-56054

Application

2-Amino-4-fluoropyridine serves as a key intermediate in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and antimicrobial agents. Its fluorine moiety enhances metabolic stability in drug candidates, while the amino group facilitates further functionalization via cross-coupling reactions. Researchers utilize this compound in palladium-catalyzed aminations and as a scaffold for fluorescent probes in biochemical assays.

Safety and Hazards

GHS Hazard Statements

  • H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (25%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (75%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H318 (25%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H319 (75%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (25%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (50%)
  • Acute Tox. 4 (25%)
  • Skin Irrit. 2 (75%)
  • Eye Dam. 1 (25%)
  • Eye Irrit. 2 (75%)
  • Acute Tox. 4 (25%)
  • STOT SE 3 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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