Description

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole (CAS: 942070-72-6) is a high-purity boronic ester derivative with the molecular formula C₁₀H₁₇BN₂O₂. This compound features a protected boronic acid group in the form of a pinacol ester, enhancing its stability and reactivity for Suzuki-Miyaura cross-coupling reactions. Its imidazole core structure makes it a versatile intermediate in pharmaceutical and agrochemical synthesis. Ideal for researchers, this product is rigorously tested for quality, ensuring optimal performance in organoboron chemistry applications. Available in various quantities with detailed analytical data (NMR, HPLC, MS) upon request.

Properties

• CAS Number: 942070-72-6
• Complexity: 242
• IUPAC Name: 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazole
• InChI: InChI=1S/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-12-7-13(8)5/h6-7H,1-5H3
• InChI Key: SNKPPKAANOYIRX-UHFFFAOYSA-N
• Exact Mass: 208.1383080
• Molecular Formula: C10H17BN2O2
• Molecular Weight: 208.07
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN=CN2C
• Topological: 36.3
• Monoisotopic Mass: 208.1383080
• Synonyms: 942070-72-6, 1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-IMIDAZOLE, DTXSID80648388, DTXCID70599138, 1-METHYL-1H-IMIDAZOLE-5-BORONIC ACID PINACOL ESTER, 1-Methylimidazole-5-boronic Acid Pinacol Ester, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazole, 1-Methyl-1H-imidazole-5-boronic acid pinacol este, MFCD11846349, (3-Methylimidazol-4-yl)boronic acid pinacol ester, 1-Methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1h-imidazole, 1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole, SCHEMBL3282058, SNKPPKAANOYIRX-UHFFFAOYSA-N, AC1345, BBL103616, STL557426, AKOS016007538, AB64622, CS-W021355, AS-55678, DA-16675, FM170536, SY014902, EN300-90584, 1-Methylimidazole-5-boronic acid, pinacol ester

Application

This compound is widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl and heteroaryl compounds. Its stability under diverse reaction conditions makes it suitable for pharmaceutical and materials science research. Additionally, it serves as a building block in the development of novel imidazole-based ligands and catalysts.

Safety and Hazards

GHS Hazard Statements

• H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (33.3%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (33.3%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (66.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (33.3%)
• Acute Tox. 4 (33.3%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (66.7%)
• Acute Tox. 4 (33.3%)
• STOT SE 3 (66.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.