Atomfair 3,3-Difluorocyclopentan-1-amine hydrochloride C5H10ClF2N CAS 939398-48-8

Description

3,3-Difluorocyclopentan-1-amine hydrochloride (CAS No. 939398-48-8) is a high-purity organic compound with the molecular formula C₅H₁₀ClF₂N. This hydrochloride salt is a valuable building block in pharmaceutical and agrochemical research, offering a versatile cyclopentane backbone with reactive amine and fluorine functionalities. The compound is characterized by its IUPAC name 3,3-difluorocyclopentan-1-amine;hydrochloride and is supplied as a white to off-white crystalline powder. With a molecular weight of 157.59 g/mol, it is ideal for nucleophilic substitution reactions, peptide coupling, and as a precursor for fluorinated heterocycles. Our product is rigorously tested for identity, purity, and stability, ensuring reliable performance in your synthetic workflows. Available in research quantities with optional custom packaging and purity grades (≥95% by HPLC).

Properties

• CAS Number: 939398-48-8
• Complexity: 92.4
• IUPAC Name: 3,3-difluorocyclopentanamine;hydrochloride
• InChI: InChI=1S/C5H9F2N.ClH/c6-5(7)2-1-4(8)3-5;/h4H,1-3,8H2;1H
• InChI Key: IIUHMNFTPGBLCX-UHFFFAOYSA-N
• Exact Mass: 157.0469833
• Molecular Formula: C5H10ClF2N
• Molecular Weight: 157.59
• SMILES: C1CC(CC1N)(F)F.Cl
• Topological: 26
• Monoisotopic Mass: 157.0469833
• Synonyms: 939398-48-8, 3,3-difluorocyclopentan-1-amine hydrochloride, 818-748-9, 3,3-DIFLUOROCYCLOPENTANAMINE HYDROCHLORIDE, 3,3-DIFLUOROCYCLOPENTANAMINE HCL, 3,3-difluorocyclopentan-1-amine;hydrochloride, MFCD15526665, (1R)-3,3-Difluorocyclopentanamine hydrochloride, (1S)-3,3-Difluorocyclopentanamine hydrochloride, MFCD15527039, MFCD23106013, MFCD23106014, 3,3-Difluorocyclopentanaminehydrochloride, 3,3-Difluorocyclopentanamine hydrochloride, 98%, SCHEMBL758317, BCP10234, 3,3-Difluorocyclopentan-1-amine HCl, AKOS016011498, PB25527, SB19902, SB20714, SB20715, 3,3-difluorocyclopentylamine hydrochloride, AS-41305, SY039476, SY059161, SY059258, DB-079730, CS-0038956, EN300-109808, F8880-2332

Application

3,3-Difluorocyclopentan-1-amine hydrochloride serves as a key intermediate in medicinal chemistry for the development of fluorinated bioactive molecules. Its rigid cyclopentane structure and fluorine substituents make it valuable for modulating lipophilicity and metabolic stability in drug candidates. The compound is particularly useful in CNS-targeting pharmaceuticals due to its ability to enhance blood-brain barrier penetration. Researchers also employ it in the synthesis of fluorinated analogs for structure-activity relationship (SAR) studies.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.