Description
7-Methyladenine (CAS No. 935-69-3) is a methylated derivative of adenine, a fundamental purine nucleobase. With the molecular formula C6H7N5 and IUPAC name 7-methylpurin-6-amine, this compound is a valuable biochemical reagent used in nucleic acid research, epigenetics, and enzymatic studies. It serves as a key reference standard for studying DNA methylation, repair mechanisms, and mutagenesis. Our high-purity 7-Methyladenine is rigorously tested via HPLC, NMR, and mass spectrometry to ensure ≥98% purity, making it ideal for sensitive analytical applications. Available in stable crystalline form, it is packaged under inert conditions to guarantee long-term integrity.
Properties
- CAS Number: 935-69-3
- Complexity: 150
- IUPAC Name: 7-methylpurin-6-amine
- InChI: InChI=1S/C6H7N5/c1-11-3-10-6-4(11)5(7)8-2-9-6/h2-3H,1H3,(H2,7,8,9)
- InChI Key: HCGHYQLFMPXSDU-UHFFFAOYSA-N
- Exact Mass: 149.07014524
- Molecular Formula: C6H7N5
- Molecular Weight: 149.15
- SMILES: CN1C=NC2=NC=NC(=C21)N
- Topological: 69.6
- Monoisotopic Mass: 149.07014524
- Physical Description: Solid
- Synonyms: 7-Methyladenine, 935-69-3, 7-Methyl-7H-purin-6-amine, 6-Amino-7-methylpurine, N7-Methyladenine, Adenine, 7-methyl-, DTXSID9049376, CHEBI:28921, NSC 7857, DTXCID6029335, Adenine, 7-methyl-(8CI), 635-651-5, 7H-Purin-6-amine, 7-methyl-, 7-methylpurin-6-amine, MFCD00127790, 7H-Purin-6-amine, 7-methyl- (9CI), CHEMBL449346, 7-Methyl-7H-adenine, 7-Methyladenine, 97%, 7-methylpurine-6-ylamine, 7-methyl-N7-Methyladenine, purine, 6-amino-7-methyl-, SCHEMBL26976, 7-Methyl-7H-purin-6-ylamine, SCHEMBL1378254, SCHEMBL6154637, 7-Methyl-7H-purin-6-amine #, NSC7857, HCGHYQLFMPXSDU-UHFFFAOYSA-N, NSC-7857, Tox21_202951, BDBM50240579, AKOS000320617, AKOS006378195, FM10148, NCGC00260497-01, CAS-935-69-3, SY250877, TS-00058, DB-307392, HY-116496, CS-0065644, NS00004081, ST50298865, 7-methyl-7H-purin-6-amine (ACD/Name 4.0), C02241, E78616, EN300-106045, 7-methyl-7H-purin-6-ylamine (ACD/Name 4.0), Q27103966, Z1203578068
Application
7-Methyladenine is widely utilized in epigenetic research to investigate DNA alkylation damage and repair pathways. It acts as a biomarker for oxidative stress studies and is employed in enzymatic assays involving methyltransferases and glycosylases. Researchers also use it to probe the structural and functional impacts of base methylation in nucleic acids.
Safety and Hazards
GHS Hazard Statements
- H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
- H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statements
- P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P333+P317, P337+P317, P362+P364, and P501
Hazard Classes and Categories
- Acute Tox. 4 (100%)
- Skin Sens. 1 (100%)
- Eye Irrit. 2A (100%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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