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Atomfair B-(2-Iodo-5-methoxyphenyl)boronic acid C7H8BIO3 CAS 89694-50-8

B-(2-Iodo-5-methoxyphenyl)boronic acid (CAS No. 89694-50-8) is a high-purity boronic acid derivative with the molecular formula C7H8BIO3. This compound features a boronic acid functional group attached to a 2-iodo-5-methoxyphenyl scaffold, making it a valuable building block for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations. Its iodine substituent enhances reactivity in aryl-aryl bond formations, while the methoxy group provides electronic modulation for selective coupling. Ideal for pharmaceutical research, material science, and organic synthesis, this reagent is supplied as a white to off-white crystalline powder with ≥95% purity (HPLC). Store under inert conditions at 2-8°C to maintain stability.

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Description

B-(2-Iodo-5-methoxyphenyl)boronic acid (CAS No. 89694-50-8) is a high-purity boronic acid derivative with the molecular formula C7H8BIO3. This compound features a boronic acid functional group attached to a 2-iodo-5-methoxyphenyl scaffold, making it a valuable building block for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations. Its iodine substituent enhances reactivity in aryl-aryl bond formations, while the methoxy group provides electronic modulation for selective coupling. Ideal for pharmaceutical research, material science, and organic synthesis, this reagent is supplied as a white to off-white crystalline powder with ≥95% purity (HPLC). Store under inert conditions at 2-8°C to maintain stability.

Properties

  • CAS Number: 89694-50-8
  • Complexity: 145
  • IUPAC Name: (2-iodo-5-methoxy-phenyl)boronic acid
  • InChI: InChI=1S/C7H8BIO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,10-11H,1H3
  • InChI Key: XQYAEIDOJUNIGY-UHFFFAOYSA-N
  • Exact Mass: 277.96112
  • Molecular Formula: C7H8BIO3
  • Molecular Weight: 277.85
  • SMILES: B(C1=C(C=CC(=C1)OC)I)(O)O
  • Topological: 49.7
  • Monoisotopic Mass: 277.96112
  • Synonyms: (2-iodo-5-methoxyphenyl)boronic acid, 89694-50-8, DTXSID801281736, B-(2-Iodo-5-methoxyphenyl)boronic acid, DTXCID301712182, 806-783-2, 2-Iodo-5-methoxyphenylboronic acid, MFCD26793796, MIBA, 5-Methoxy-2-iodophenylboronic acid, SCHEMBL9935773, MIBA, 96%, XQYAEIDOJUNIGY-UHFFFAOYSA-N, (2-iodo-5-methoxyphenyl)boronicacid, AKOS025392343, AS-2728, 2-IODO-5-METHOXYPHENYLBORONICACID, SY040731, DB-293177, CS-0150494, N12352

Application

B-(2-Iodo-5-methoxyphenyl)boronic acid is widely used in Suzuki-Miyaura cross-coupling reactions to synthesize biaryl compounds for drug discovery and materials science. Its iodine substituent facilitates sequential functionalization in multi-step syntheses. The methoxy group directs electrophilic aromatic substitutions, enabling regioselective modifications. Researchers also employ it in the development of boron-based sensors and covalent organic frameworks (COFs).

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]

Precautionary Statements

  • P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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