Description

6-Bromo-3-methylpyridin-2-amine (CAS No. 89466-16-0) is a high-purity heterocyclic organic compound with the molecular formula C₆H₇BrN₂. This brominated pyridine derivative is a valuable building block in pharmaceutical and agrochemical research, offering versatile reactivity for cross-coupling reactions, nucleophilic substitutions, and other synthetic transformations. The compound features a reactive bromine substituent at the 6-position and an amino group at the 2-position, making it an ideal intermediate for the synthesis of complex molecules. Supplied as a crystalline solid with ≥95% purity (HPLC), it is rigorously tested for consistency and stability. Suitable for use in medicinal chemistry, material science, and catalysis research. Store under inert conditions at 2-8°C to maintain optimal stability.

Properties

• CAS Number: 89466-16-0
• Complexity: 97.1
• IUPAC Name: 6-bromo-3-methyl-pyridin-2-amine
• InChI: InChI=1S/C6H7BrN2/c1-4-2-3-5(7)9-6(4)8/h2-3H,1H3,(H2,8,9)
• InChI Key: ANDWKDRELVPNDM-UHFFFAOYSA-N
• Exact Mass: 185.97926
• Molecular Formula: C6H7BrN2
• Molecular Weight: 187.04
• SMILES: CC1=C(N=C(C=C1)Br)N
• Topological: 38.9
• Monoisotopic Mass: 185.97926
• Synonyms: 6-BROMO-3-METHYLPYRIDIN-2-AMINE, 89466-16-0, 6-Bromo-3-methyl-2-pyridinamine, 2-AMINO-6-BROMO-3-METHYLPYRIDINE, MFCD17014961, SCHEMBL2673083, ANDWKDRELVPNDM-UHFFFAOYSA-N, 6-Bromo-3-methylpyridin-2-ylamine, AKOS024260010, AB71668, CS-W007289, DS-7301, SY058796, DB-113931, EN300-100966, 6-bromo-3-methyl-pyridin-2-ylamine; 2-Amino-6-brom-3-methyl-pyridin;

Application

6-Bromo-3-methylpyridin-2-amine serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and receptor modulators. Its reactive bromine and amino groups enable efficient participation in Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions. Researchers utilize this compound to construct pyridine-based scaffolds for drug discovery programs targeting CNS disorders and inflammatory diseases. It is also employed in material science for the preparation of functionalized ligands in coordination chemistry.

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