Description

7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CAS No. 882521-63-3) is a high-purity heterocyclic compound with the molecular formula C₆H₅BrN₄. This specialized chemical features a brominated [1,2,4]triazolo[1,5-a]pyridine scaffold with an amine functional group at the 2-position, making it a valuable intermediate for pharmaceutical and agrochemical research. The compound is supplied as a crystalline solid with ≥95% purity (HPLC) and is rigorously tested for consistency in quality. Ideal for cross-coupling reactions, scaffold diversification, and medicinal chemistry applications, this product is packaged under inert conditions to ensure stability. Available in quantities from milligrams to kilograms, it comes with comprehensive analytical data including ¹H NMR, ¹³C NMR, and mass spectrometry reports.

Properties

• CAS Number: 882521-63-3
• Complexity: 154
• IUPAC Name: 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
• InChI: InChI=1S/C6H5BrN4/c7-4-1-2-11-5(3-4)9-6(8)10-11/h1-3H,(H2,8,10)
• InChI Key: DAYYXZOMYRSLBX-UHFFFAOYSA-N
• Exact Mass: 211.96976
• Molecular Formula: C6H5BrN4
• Molecular Weight: 213.03
• SMILES: C1=CN2C(=NC(=N2)N)C=C1Br
• Topological: 56.2
• Monoisotopic Mass: 211.96976
• Synonyms: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine, 7-bromo-(1,2,4)triazolo(1,5-a)pyridin-2-amine, 835-295-2, 882521-63-3, 2-AMINO-7-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE, 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine, MFCD11846606, 7-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine, [1,2,4]Triazolo[1,5-a]pyridin-2-amine, 7-bromo-, SCHEMBL42128, DTXSID00712398, DAYYXZOMYRSLBX-UHFFFAOYSA-N, BCP07699, AKOS015919551, CS-W008673, DS-1651, FS-3344, PB32995, DA-16895, FB140382, SY017188, EN300-79736, 7-Bromo[1,2,4]triazolo[1,5-a]pyridine-2-amine, Z1217131079, 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine, AldrichCPR, 7-Bromo-[1 pound not2 pound not4]triazolo[1 pound not5-a]pyridin-2-amine

Application

7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine serves as a key building block in the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and antimicrobial agents. Its bromine moiety enables efficient palladium-catalyzed cross-coupling reactions for structural diversification. Researchers utilize this compound in fragment-based drug discovery due to its privileged triazolopyridine core. The amine functionality allows for further derivatization via amide formation or reductive alkylation strategies.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.