Description

Phthaloyl Chloride (CAS No. 88-95-9) is a high-purity aromatic dicarbonyl chloride widely used in organic synthesis and polymer chemistry. With the molecular formula C₈H₄Cl₂O₂ and IUPAC name benzene-1,2-dicarbonyl chloride, this reactive intermediate features two acyl chloride groups positioned ortho to each other on a benzene ring, enabling its use in condensation reactions, peptide coupling, and polymer formation. Our product is rigorously tested for consistency, offering ≥98% purity (GC) with minimal moisture content to ensure optimal reactivity. Supplied in amber glass bottles or sealed drums under inert gas to prevent hydrolysis, it is ideal for synthesizing phthalocyanine dyes, polyimides, and pharmaceutical precursors. Handle with care in a controlled environment due to its moisture-sensitive and corrosive nature.

Properties

• CAS Number: 88-95-9
• Complexity: 181
• IUPAC Name: benzene-1,2-dicarbonyl chloride
• InChI: InChI=1S/C8H4Cl2O2/c9-7(11)5-3-1-2-4-6(5)8(10)12/h1-4H
• InChI Key: FYXKZNLBZKRYSS-UHFFFAOYSA-N
• Exact Mass: 201.9588348
• Molecular Formula: C8H4Cl2O2
• Molecular Weight: 203.02
• SMILES: C1=CC=C(C(=C1)C(=O)Cl)C(=O)Cl
• Topological: 34.1
• Monoisotopic Mass: 201.9588348
• Physical Description: Colorless oily liquid; mp = 15-16 deg C; Colorless or yellow liquid; mp = 6-12 deg C;
• Synonyms: Phthaloyl dichloride, PHTHALOYL CHLORIDE, 88-95-9, o-Phthaloyl dichloride, Phthalic chloride, Phthalic dichloride, Phthalyl chloride, Phthalyl dichloride, Phthalic acid dichloride, 1,2-Benzenedicarbonyl dichloride, 1,2-Bis(chlorocarbonyl)benzene, 1,2-Phthaloyl dichloride, NSC 44611, EINECS 201-869-0, 8S64APH24W, CCRIS 8625, NSC-44611, PHTHALOYL CHLORIDE [MI], DTXSID8038691, O-PHTHALIC ACID DICHLORIDE, EC 201-869-0, Phthaloyl chloride (8CI), 1,2Bis(chlorocarbonyl)benzene, 1,2Benzenedicarbonyl dichloride, DTXCID6018691, 201-869-0, benzene-1,2-dicarbonyl chloride, benzene-1,2-dicarbonyl dichloride, Phthaloyldichloride, MFCD00000666, UNII-8S64APH24W, Pthaloyl chloride, phthalic dichoride, Phthaloyl chloride, 90%, SCHEMBL422, NSC44611, STR02496, SBB060270, STL453643, TD1160, AKOS009029113, Phthaloyl chloride, technical, >=90%, DB-057111, NS00002449, P0405, ST51046490, EN300-19274, A15044, A843009, Q27270948, F1905-7003

Application

Phthaloyl chloride serves as a key reagent in the synthesis of high-performance polymers such as polyimides and polyamides due to its bifunctional reactivity. It is widely employed in peptide coupling reactions and the production of phthalocyanine dyes for pigments and coatings. Researchers also utilize it to prepare anhydrides, esters, and amides in fine chemical and pharmaceutical manufacturing.

Safety and Hazards

GHS Hazard Statements

• H290 (44.9%): May be corrosive to metals [Warning Corrosive to Metals]
• H312 (62%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H314 (99.6%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
• H317 (47%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H318 (46.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H334 (47%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
• H335 (69.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P233, P234, P260, P261, P264, P264+P265, P271, P272, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P333+P317, P342+P316, P362+P364, P363, P390, P403, P403+P233, P405, P406, and P501

Hazard Classes and Categories

• Met. Corr. 1 (44.9%)
• Acute Tox. 4 (62%)
• Skin Corr. 1B (99.6%)
• Skin Sens. 1 (47%)
• Eye Dam. 1 (46.2%)
• Resp. Sens. 1 (47%)
• STOT SE 3 (69.2%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.