Atomfair

Awaiting product image

Atomfair 5-Trifluoromethyl-pyrazolo[1,5-a]pyridine-2-carboxylic acid C9H5F3N2O2 CAS 876379-73-6

5-Trifluoromethyl-pyrazolo[1,5-a]pyridine-2-carboxylic acid (CAS No. 876379-73-6) is a high-purity heterocyclic compound with the molecular formula C9H5F3N2O2, designed for advanced research applications. This trifluoromethyl-substituted pyrazolopyridine derivative is characterized by its carboxylic acid functional group, making it a versatile intermediate in medicinal chemistry and pharmaceutical development. Its unique structure contributes to enhanced metabolic stability and binding affinity in drug discovery. Available in >98% purity (HPLC), this compound is supplied as a fine white to off-white powder, rigorously tested via NMR, LC-MS, and elemental analysis to ensure consistency. Ideal for use in high-throughput screening, lead optimization, and structure-activity relationship (SAR) studies. Store under inert…

Category:

Description

5-Trifluoromethyl-pyrazolo[1,5-a]pyridine-2-carboxylic acid (CAS No. 876379-73-6) is a high-purity heterocyclic compound with the molecular formula C9H5F3N2O2, designed for advanced research applications. This trifluoromethyl-substituted pyrazolopyridine derivative is characterized by its carboxylic acid functional group, making it a versatile intermediate in medicinal chemistry and pharmaceutical development. Its unique structure contributes to enhanced metabolic stability and binding affinity in drug discovery. Available in >98% purity (HPLC), this compound is supplied as a fine white to off-white powder, rigorously tested via NMR, LC-MS, and elemental analysis to ensure consistency. Ideal for use in high-throughput screening, lead optimization, and structure-activity relationship (SAR) studies. Store under inert conditions at -20°C for long-term stability.

Properties

  • CAS Number: 876379-73-6
  • Complexity: 295
  • IUPAC Name: 5-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid
  • InChI: InChI=1S/C9H5F3N2O2/c10-9(11,12)5-1-2-14-6(3-5)4-7(13-14)8(15)16/h1-4H,(H,15,16)
  • InChI Key: MQOFNRWEIYQKPP-UHFFFAOYSA-N
  • Exact Mass: 230.03031189
  • Molecular Formula: C9H5F3N2O2
  • Molecular Weight: 230.14
  • SMILES: C1=CN2C(=CC(=N2)C(=O)O)C=C1C(F)(F)F
  • Topological: 54.6
  • Monoisotopic Mass: 230.03031189
  • Synonyms: 5-trifluoromethyl-pyrazolo[1,5-a]pyridine-2-carboxylic acid, 876379-73-6, SCHEMBL4910976, MQOFNRWEIYQKPP-UHFFFAOYSA-N

Application

This compound serves as a key building block in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and antiviral agents. Its trifluoromethyl group enhances lipophilicity and electron-withdrawing properties, making it valuable for modulating drug pharmacokinetics. Researchers utilize it in fragment-based drug design (FBDD) and as a scaffold for targeted therapeutics in oncology and CNS disorders.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products