Description

(S)-(+)-3-Hydroxytetrahydrofuran (CAS: 86087-23-2) is a high-purity chiral compound with the molecular formula C₄H₈O₂, widely utilized in pharmaceutical synthesis, asymmetric catalysis, and fine chemical research. This enantiomerically enriched building block is characterized by its hydroxytetrahydrofuran scaffold, offering versatile reactivity for the construction of complex molecular architectures. Available in >98% chemical purity (HPLC/GC), it is supplied in rigorously controlled conditions to ensure stability and performance. Ideal for researchers requiring stereoselective intermediates, this product is extensively validated for use in medicinal chemistry, agrochemical development, and material science applications. Packaging options range from milligrams to kilograms, with custom solutions available for bulk orders.

Properties

• CAS Number: 86087-23-2
• Complexity: 44.8
• IUPAC Name: (3S)-tetrahydrofuran-3-ol
• InChI: InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m0/s1
• InChI Key: XDPCNPCKDGQBAN-BYPYZUCNSA-N
• Exact Mass: 88.052429494
• Molecular Formula: C4H8O2
• Molecular Weight: 88.11
• SMILES: C1COC[C@H]1O
• Topological: 29.5
• Monoisotopic Mass: 88.052429494
• Synonyms: (S)-(+)-3-Hydroxytetrahydrofuran, 86087-23-2, (S)-3-Hydroxytetrahydrofurane, DTXSID50893863, (+)-3-HYDROXYTETRAHYDROFURAN, DTXCID401323902, 425-090-2, 617-795-0, (3S)-oxolan-3-ol, (S)-Tetrahydrofuran-3-ol, (S)-3-Hydroxytetrahydrofuran, (S)-TETRAHYDRO-3-FURANOL, (S)-(+)-Tetrahydro-3-furanol, 3-Furanol, tetrahydro-, (3S)-, MFCD00064327, (S) 3-Hydroxytetrahydrofuran, s-(+)-3-hydroxytetrahydrofuran, (3S)-TETRAHYDROFURAN-3-OL, (3S)oxolan-3-ol, Tetrahydro-3-furanol #, (3s)-tetrahydro-3-furanol, (S)-Tetrahydro-furan-3-ol, 3-(s)-hydroxytetrahydrofuran, SCHEMBL158873, SCHEMBL942278, 3E76E9MC2H, SCHEMBL6270170, SCHEMBL23572885, (S)-(+)-tetrahydrofuran-3-ol, 3-Hydroxytetrahydrofuran, (+)-, 3-Hydroxytetrahydrofuran, (S)-, (+)-(s)-3-hydroxytetrahydrofuran, (S)-(+)3-hydroxy-tetrahydrofuran, CS-D0600, (S)-(+)-3-hydroxy-tetrahydrofuran, AC-491, SBB062959, (S)-(+)-3-hydroxy-tetrahydrofurane, AKOS005145535, AKOS015908999, AC-1844, FH24508, PS-9362, HY-76476, T1716, EN300-172677, 3S-Hydroxytetrahydrofuran;(S)-Tetrahydro-3-furanol;(+)-3-Hydroxytetrahydrofuran

(S)-(+)-3-Hydroxytetrahydrofuran serves as a key chiral synthon in the asymmetric synthesis of bioactive molecules, including antiviral and anticancer agents. It is employed as a ligand precursor in transition-metal catalysis for enantioselective transformations. The compound also finds utility in polymer chemistry as a monomer for biodegradable materials. Its stereochemical integrity makes it valuable for studying enzyme-substrate interactions in biochemical assays.

Safety and Hazards

GHS Hazard Statements

• H315 (98.2%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (98.2%)
• Eye Irrit. 2 (98.2%)
• STOT SE 3 (96.4%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.