Description

7-Fluoroprostacyclin (CAS: 84217-11-8) is a fluorinated analog of prostacyclin (PGI₂), a potent vasodilator and inhibitor of platelet aggregation. This high-purity compound, with the molecular formula C₂₀H₃₁FO₅, is designed for advanced biochemical and pharmacological research. Its IUPAC name is (5Z)-5-[(3aR,4R,5R,6aR)-3-fluoro-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid. 7-Fluoroprostacyclin is particularly valuable for studying the role of prostacyclin derivatives in cardiovascular physiology, endothelial function, and thrombosis. The compound is supplied as a lyophilized powder or in solution, with strict quality control to ensure batch-to-batch consistency. Store at -20°C under inert atmosphere for optimal stability.

Properties

• CAS Number: 84217-11-8
• Complexity: 518
• IUPAC Name: (5Z)-5-[(3aR,4R,5R,6aR)-3-fluoro-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
• InChI: InChI=1S/C20H31FO5/c1-2-3-4-7-13(22)10-11-14-15(23)12-17-19(14)20(21)16(26-17)8-5-6-9-18(24)25/h8,10-11,13-15,17,19-20,22-23H,2-7,9,12H2,1H3,(H,24,25)/b11-10+,16-8-/t13-,14-,15+,17+,19+,20?/m0/s1
• InChI Key: PICZVWWLSUAEJF-QCODSTRBSA-N
• Exact Mass: 370.21555225
• Molecular Formula: C20H31FO5
• Molecular Weight: 370.5
• SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]2[C@@H]1C(/C(=C/CCCC(=O)O)/O2)F)O)O
• Topological: 87
• Monoisotopic Mass: 370.21555225
• Synonyms: 7-Fluoroprostacyclin, Pgi2-7-F, 84217-11-8, Prosta-5,13-dien-1-oic acid, 6,9-epoxy-7-fluoro-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-

Application

7-Fluoroprostacyclin is widely used in cardiovascular research to investigate the mechanisms of vasodilation and platelet inhibition. It serves as a stable analog of prostacyclin for studying receptor binding and signal transduction pathways in endothelial cells. Researchers utilize this compound to explore therapeutic interventions for hypertension, pulmonary arterial hypertension, and thrombotic disorders. Its fluorinated structure enhances metabolic stability compared to native prostacyclin, making it valuable for in vitro and ex vivo studies.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.