Description

4-Nitrophenyl Acetate (CAS: 830-03-5) is a high-purity biochemical reagent widely used in enzymatic assays and research applications. This compound, with the molecular formula C₈H₇NO₄, serves as a chromogenic substrate for esterases, lipases, and other hydrolytic enzymes, producing the yellow-colored 4-nitrophenol upon cleavage. Its excellent stability and sensitivity make it ideal for kinetic studies, enzyme characterization, and high-throughput screening. Supplied as a crystalline solid, our 4-Nitrophenyl Acetate is rigorously tested to ensure ≥99% purity (GC) and is packaged under inert conditions to maintain integrity. Suitable for laboratory use only.

Properties

• CAS Number: 830-03-5
• Complexity: 203
• IUPAC Name: (4-nitrophenyl) acetate
• InChI: InChI=1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
• InChI Key: QAUUDNIGJSLPSX-UHFFFAOYSA-N
• Exact Mass: 181.03750770
• Molecular Formula: C8H7NO4
• Molecular Weight: 181.15
• SMILES: CC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]
• Topological: 72.1
• Monoisotopic Mass: 181.03750770
• Physical Description: White crystalline solid;
• Vapor Pressure: 0.00186 [mmHg]
• Synonyms: 4-Nitrophenyl acetate, 830-03-5, p-Acetoxynitrobenzene, P-NITROPHENYL ACETATE, Acetic acid, 4-nitrophenyl ester, p-Nitrophenyl acetate (VAN), NSC 2633, para-nitrophenyl acetate, EINECS 212-593-5, UNII-I902J0QH9S, BRN 0515874, I902J0QH9S, CHEBI:82635, PNP-ACETATE, AI3-00496, NSC-2633, 4-O2NC6H4OAc, P-ACETOXY NITROBENZEN, P-NITROPHENYL ACETATES, DTXSID2061191, 4-06-00-01298 (Beilstein Handbook Reference), pAcetoxynitrobenzene, pNitrophenol acetate, pNitrophenyl acetate, Acetic acid pnitrophenyl ester, Acetic acid, pnitrophenyl ester, Acetic acid, 4nitrophenyl ester, DTXCID0048341, qauudnigjslpsx-uhfffaoysa-n, p-Nitrophenol acetate, (4-nitrophenyl) acetate, Acetic acid, p-nitrophenyl ester, Acetic acid p-nitrophenyl ester, Acetic acid 4-nitrophenyl ester, MFCD00007326, p-Nitrobenzene acetate, Phenol, p-nitro-, acetate, Acetic acid 4-nitro-phenyl ester, WLN: WNR DOV1, SCHEMBL74985, CHEMBL40988, SCHEMBL3891925, BDBM11326, NSC2633, SBB064125, AKOS015833423, CS-W017169, FN00583, 4-Nitrophenyl acetate, esterase substrate, AS-19298, SY010750, 4-Nitrophenyl acetate, >=99.0% (GC), DB-056674, A0040, NS00022825, ST50826622, F31024, Q27156150, K4V

4-Nitrophenyl Acetate is primarily employed as a substrate for detecting esterase and lipase activity in biochemical assays. It is commonly used in enzyme kinetics studies due to its ability to release 4-nitrophenol, which can be quantified spectrophotometrically at 405 nm. This compound is also utilized in diagnostic applications and pharmaceutical research to evaluate enzyme inhibitors. Its high sensitivity and stability make it a preferred choice for both academic and industrial laboratories.

Safety and Hazards

GHS Hazard Statements

• H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]
• H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

• P210, P220, P261, P264+P265, P272, P280, P302+P352, P305+P354+P338, P317, P321, P333+P317, P362+P364, P370+P378, and P501

Hazard Classes and Categories

• Ox. Sol. 3 (100%)
• Skin Sens. 1 (100%)
• Eye Dam. 1 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.