Description

(1R)-1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-ol (CAS: 80418-12-8) is a high-purity chiral fluorinated alcohol derivative with the molecular formula C₈H₆BrF₃O. This compound features a stereogenic center at the 1-position, making it a valuable building block for asymmetric synthesis and pharmaceutical intermediates. Its bromophenyl and trifluoroethanol functional groups enhance reactivity in cross-coupling reactions, nucleophilic substitutions, and as a precursor for bioactive molecules. Ideal for researchers in medicinal chemistry, catalysis, and material science, this product is rigorously tested for purity (typically ≥95% by HPLC or GC) and supplied with comprehensive analytical data (NMR, MS, IR). Store under inert conditions at 2-8°C to maintain stability.

Properties

• CAS Number: 80418-12-8
• Complexity: 163
• IUPAC Name: (1R)-1-(4-bromophenyl)-2,2,2-trifluoro-ethanol
• InChI: InChI=1S/C8H6BrF3O/c9-6-3-1-5(2-4-6)7(13)8(10,11)12/h1-4,7,13H/t7-/m1/s1
• InChI Key: PHWPRSZULISLMK-SSDOTTSWSA-N
• Exact Mass: 253.95541
• Molecular Formula: C8H6BrF3O
• Molecular Weight: 255.03
• SMILES: C1=CC(=CC=C1[C@H](C(F)(F)F)O)Br
• Topological: 20.2
• Monoisotopic Mass: 253.95541
• Synonyms: 80418-12-8, DTXSID10505334, (1R)-1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-ol, DTXCID00456144, (R)-1-(4-bromophenyl)-2,2,2-trifluoroethanol, (1R)-1-(4-bromophenyl)-2,2,2-trifluoroethanol, (R)-1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-ol, MFCD14707648, SCHEMBL1589426, FDA41812, AKOS015855370, BS-50319, DB-075682, CS-0112561, EN300-1937558

This compound serves as a versatile intermediate in the synthesis of chiral ligands, catalysts, and fluorinated pharmaceuticals. It is particularly useful in asymmetric hydrogenation and C-C bond-forming reactions. Researchers also employ it in the development of novel agrochemicals and liquid crystal materials due to its unique electronic and steric properties. Its bromophenyl moiety facilitates further functionalization via Suzuki or Heck couplings.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.