Description

2,2,2-Trifluoroethylamine (CAS No. 753-90-2) is a highly versatile fluorinated amine compound with the molecular formula C₂H₄F₃N. This colorless to pale yellow liquid is widely used in pharmaceutical synthesis, agrochemical manufacturing, and advanced material research due to its strong electron-withdrawing trifluoromethyl group. With a purity of ≥98% (GC), our product is rigorously tested to meet the highest industry standards, ensuring optimal performance in your applications. It is packaged under inert gas to maintain stability and shipped with detailed technical documentation, including MSDS and Certificate of Analysis. Ideal for nucleophilic substitution reactions, amide couplings, and as a building block in medicinal chemistry.

Properties

• CAS Number: 753-90-2
• Complexity: 38.5
• IUPAC Name: 2,2,2-trifluoroethanamine
• InChI: InChI=1S/C2H4F3N/c3-2(4,5)1-6/h1,6H2
• InChI Key: KIPSRYDSZQRPEA-UHFFFAOYSA-N
• Exact Mass: 99.02958362
• Molecular Formula: C2H4F3N
• Molecular Weight: 99.06
• SMILES: C(C(F)(F)F)N
• Topological: 26
• Monoisotopic Mass: 99.02958362
• Dissociation Constants: 5.7
• Synonyms: 2,2,2-Trifluoroethylamine, 753-90-2, Ethanamine, 2,2,2-trifluoro-, ETHYLAMINE, 2,2,2-TRIFLUORO-, EINECS 212-041-3, BRN 1733204, DTXSID6061070, 4-04-00-00442 (Beilstein Handbook Reference), DTXCID3047768, 212-041-3, Trifluoroethylamine, 2,2,2-Trifluoroethanamine, 2,2,2-trifluoroethan-1-amine, 2-Amino-1,1,1-trifluoroethane, 2,2,2-trifluoro-1-aminoethane, ethane, 1-amino-2,2,2-trifluoro-, MFCD00008132, 2,2,2-trifluoroethyl amine, C2H4F3N, 1-Amino-2,2,2-trifluoroethane, trifluoro ethylamine, trifluoroethyl amine, 2,2,2-trifluorethylamine, 2,2,2-trifluroethylamine, CF3CH2NH2, 2.2.2-trifluoroethylamine, SCHEMBL6992, 2,2,2,-trifluroethylamine, 2,2,2-trifluoroethaneamine, 2,2,2-Trifluoro-ethanamin, 2, 2,2-trifluoroethylamine, 2,2,2,-trifluoroethanamine, 2,2,2,-trifluoroethylamine, 2,2,2-trifluoro ethylamine, 2,2,2-trifluoro-ethylamine, 2,2,2-trifluoroethanaminium, SCHEMBL68151, 2,2,2-trifluoroethane amine, (2,2,2-trifluoroethyl)amine, 2,2,2-trifluoro ethyl amine, 2,2,2-trifluoro-ethyl amine, 2,2,2-trifluoro-ethyl-amine, 2,2,2-Trifluoroethanamine #, 44H2STW5P2, SCHEMBL1345990, SCHEMBL2958774, 2,2,2-Trifluoro-1-ethanamine, CHEMBL1162282, (2,2,2-trifluoro-ethyl)-amine, beta,beta,beta-Trifluoroethylamine, STR03274, FD2012, STL484274, 2,2,2-Trifluoroethylamine, 99.5%, AKOS002528576, PB47403, .beta.,.beta.,.beta.-Trifluoroethylamine, BP-10752, DB-001190, NS00079909, T1169, EN300-34159, 2,2,2-Trifluoroethylamine, >=98.0% (GC), F2190-0538

2,2,2-Trifluoroethylamine is a key intermediate in the synthesis of pharmaceuticals, particularly for introducing the trifluoroethyl moiety into drug candidates. It is used in agrochemical production to enhance the bioavailability of active ingredients. Researchers also employ it in material science to modify surface properties and in catalysis for asymmetric synthesis.

Safety and Hazards

GHS Hazard Statements

• H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H302 (84.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H314 (98.7%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P363, P370+P378, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 2 (100%)
• Acute Tox. 4 (84.6%)
• Skin Corr. 1B (98.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.