Description

2-(2-(2-Methoxyethoxy)ethoxy)ethylamine (CAS No. 74654-07-2) is a high-purity, multifunctional amine compound with the molecular formula C₇H₁₇NO₃. This clear, colorless to pale yellow liquid is characterized by its unique polyether-amine structure, featuring a terminal amine group and methoxyethoxyethoxy side chains, making it highly soluble in water and organic solvents. With a molecular weight of 163.22 g/mol, it is widely utilized in organic synthesis, polymer chemistry, and surface modification applications. Its excellent reactivity as a nucleophile and ligand makes it invaluable for pharmaceutical intermediates, corrosion inhibitors, and functionalized material synthesis. Packaged under inert gas to ensure stability, this product is rigorously tested for purity (typically ≥95% by GC) and is available in various quantities to meet both research and industrial demands.

Properties

• CAS Number: 74654-07-2
• Complexity: 70.7
• IUPAC Name: 2-[2-(2-methoxyethoxy)ethoxy]ethanamine
• InChI: InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
• InChI Key: OKUWOEKJQRUMBW-UHFFFAOYSA-N
• Exact Mass: 163.12084340
• Molecular Formula: C7H17NO3
• Molecular Weight: 163.21
• SMILES: COCCOCCOCCN
• Topological: 53.7
• Monoisotopic Mass: 163.12084340
• Synonyms: 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine, 2-[2-(2-Methoxyethoxy)ethoxy]ethylamine, 2-[2-(2-methoxyethoxy)ethoxy]ethanamine, 2-{2-(2-methoxyethoxy)ethoxy}ethylamine, EINECS 277-952-0, 2-(2-(2-Methoxyethoxy)ethoxy)ethylamine, 277-952-0, 74654-07-2, m-PEG3-Amine, mPEG3-NH2, MFCD17215909, Methyl-PEG3-amine, 1-[2-(2-AMINOETHOXY)ETHOXY]-2-METHOXYETHANE, 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine, 2-[2-(2-Methoxyethoxy)ethoxy]ethan-1-amine, m-PEG3-Amine?, Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-, SCHEMBL942035, SCHEMBL4266750, YSSJ00972, DTXSID30996169, BCP11313, AKOS013509846, CS-W018960, FM72932, GS-6416, HY-W018174, Tri(ethylene glycol) methyl ether amine, BP-20975, SY112854, 2-(2-(2-methoxyethoxy)-ethoxy)ethanamine, 2-(2-(2-Methoxyethoxy)ethoxy)-ethanamine, 2-(2-(2-methoxyethoxyl)ethoxy)ethanamine, 2-(2-(2-methoxyethoxyl)ethoxy)-ethanamine, DB-104122, NS00059699, 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethylamine, EN300-761802

Application

2-(2-(2-Methoxyethoxy)ethoxy)ethylamine is extensively used as a versatile building block in organic synthesis, particularly for creating functionalized polymers and dendrimers. Its polyether backbone and terminal amine group make it ideal for modifying surfaces, such as nanoparticles or coatings, to enhance hydrophilicity and biocompatibility. Additionally, it serves as a key intermediate in pharmaceutical research for synthesizing drug candidates with improved solubility and bioavailability.

Safety and Hazards

GHS Hazard Statements

• H314 (50%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
• H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (50%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Corr. 1C (50%)
• Skin Irrit. 2 (50%)
• Eye Dam. 1 (50%)
• Eye Irrit. 2A (50%)
• STOT SE 3 (50%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.