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Atomfair 3-Bromo-5-chloropyridine C5H3BrClN CAS 73583-39-8

3-Bromo-5-chloropyridine (CAS No. 73583-39-8) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrClN . This heteroaromatic compound is a versatile building block in pharmaceutical, agrochemical, and materials science research. Its unique structure, featuring both bromine and chlorine substituents on the pyridine ring, enables selective functionalization via cross-coupling reactions (e.g., Suzuki, Stille) or nucleophilic substitutions. Our product is rigorously tested by HPLC, GC, and NMR to ensure ≥98% purity, making it ideal for demanding synthetic applications. Supplied in amber glass vials under inert atmosphere to prevent degradation. IUPAC Name: 3-bromo-5-chloropyridine Molecular Weight: 192.44 g/mol Synonym(s): 3-Bromo-5-chloropyridine; DTXSID50345670 Storage: 2-8°C…

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Description

3-Bromo-5-chloropyridine (CAS No. 73583-39-8) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrClN. This heteroaromatic compound is a versatile building block in pharmaceutical, agrochemical, and materials science research. Its unique structure, featuring both bromine and chlorine substituents on the pyridine ring, enables selective functionalization via cross-coupling reactions (e.g., Suzuki, Stille) or nucleophilic substitutions. Our product is rigorously tested by HPLC, GC, and NMR to ensure ≥98% purity, making it ideal for demanding synthetic applications. Supplied in amber glass vials under inert atmosphere to prevent degradation.

  • IUPAC Name: 3-bromo-5-chloropyridine
  • Molecular Weight: 192.44 g/mol
  • Synonym(s): 3-Bromo-5-chloropyridine; DTXSID50345670
  • Storage: 2-8°C under nitrogen

Properties

  • CAS Number: 73583-39-8
  • Complexity: 78.8
  • IUPAC Name: 3-bromo-5-chloro-pyridine
  • InChI: InChI=1S/C5H3BrClN/c6-4-1-5(7)3-8-2-4/h1-3H
  • InChI Key: BELDOPUBSLPBCQ-UHFFFAOYSA-N
  • Exact Mass: 190.91374
  • Molecular Formula: C5H3BrClN
  • Molecular Weight: 192.44
  • SMILES: C1=C(C=NC=C1Br)Cl
  • Topological: 12.9
  • Monoisotopic Mass: 190.91374
  • Synonyms: 3-Bromo-5-chloropyridine, 73583-39-8, DTXSID50345670, DTXCID40296743, 625-376-9, 3-Chloro-5-bromopyridine, 3-Bromo-5-chloro-pyridine, MFCD04114221, Pyridine, 3-bromo-5-chloro-, 3-Bromo-5-chloropyridine #, SCHEMBL504658, SCHEMBL3414869, SCHEMBL3679157, SCHEMBL4926478, 3-Bromo-5-chloropyridine, 97%, BCP04458, AKOS005145641, AB18001, AC-5131, CS-W003165, HY-W003165, PS-6230, SY019382, DB-024232, B3608, EN300-114019

Application

3-Bromo-5-chloropyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and ligands for transition metal catalysis. Its halogenated structure facilitates the construction of complex pyridine-based scaffolds via palladium-catalyzed cross-coupling reactions. Researchers utilize this compound in the development of kinase inhibitors, antimicrobial agents, and electronic materials. The electron-withdrawing effects of both halogens enhance its reactivity in SNAr reactions, making it valuable for constructing heterocyclic libraries in drug discovery programs.

Safety and Hazards

GHS Hazard Statements

  • H301 (87.5%): Toxic if swallowed [Danger Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H318 (87.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H319 (12.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 3 (87.5%)
  • Skin Irrit. 2 (100%)
  • Eye Dam. 1 (87.5%)
  • Eye Irrit. 2 (12.5%)
  • STOT SE 3 (97.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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