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Atomfair 2-Bromo-5-iodopyridine C5H3BrIN CAS 73290-22-9

2-Bromo-5-iodopyridine (CAS No. 73290-22-9) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrIN , widely utilized in pharmaceutical, agrochemical, and materials science research. This heterocyclic compound features both bromine and iodine substituents at the 2- and 5-positions of the pyridine ring, respectively, enabling versatile cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. With a molecular weight of 283.89 g/mol, it is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring optimal performance in synthetic applications. Ideal for metal-catalyzed transformations , ligand synthesis , and API intermediates , this reagent is packaged under inert conditions to guarantee…

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Description

2-Bromo-5-iodopyridine (CAS No. 73290-22-9) is a high-purity halogenated pyridine derivative with the molecular formula C5H3BrIN, widely utilized in pharmaceutical, agrochemical, and materials science research. This heterocyclic compound features both bromine and iodine substituents at the 2- and 5-positions of the pyridine ring, respectively, enabling versatile cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. With a molecular weight of 283.89 g/mol, it is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring optimal performance in synthetic applications. Ideal for metal-catalyzed transformations, ligand synthesis, and API intermediates, this reagent is packaged under inert conditions to guarantee stability. Available in gram to kilogram quantities with optional custom purity and packaging.

Properties

  • CAS Number: 73290-22-9
  • Complexity: 78.8
  • IUPAC Name: 2-bromo-5-iodo-pyridine
  • InChI: InChI=1S/C5H3BrIN/c6-5-2-1-4(7)3-8-5/h1-3H
  • InChI Key: LLKRSJVPTKFSLS-UHFFFAOYSA-N
  • Exact Mass: 282.84936
  • Molecular Formula: C5H3BrIN
  • Molecular Weight: 283.89
  • SMILES: C1=CC(=NC=C1I)Br
  • Topological: 12.9
  • Monoisotopic Mass: 282.84936
  • Synonyms: 2-Bromo-5-iodopyridine, 73290-22-9, DTXSID00406189, DTXCID00357041, 629-182-5, MFCD03095201, 2-Bromo-5-iodo-pyridine, Pyridine, 2-bromo-5-iodo-, 5-iodo-2-bromo-pyridine, SCHEMBL502933, 2-Bromo-5-iodopyridine, 96%, LLKRSJVPTKFSLS-UHFFFAOYSA-N, SBB013974, STK688510, AKOS002665603, AC-1094, CS-W003027, FB35147, GS-6890, HY-W003027, PB14333, SY008264, DB-024230, ST4128287, B3765, EN300-88738

Application

2-Bromo-5-iodopyridine serves as a critical building block in organometallic chemistry, enabling the synthesis of complex pyridine-based scaffolds via palladium-catalyzed cross-couplings. It is employed in the development of pharmaceutical intermediates, particularly for kinase inhibitors and antiviral agents. Researchers also utilize it to construct functionalized ligands for catalysis and OLED materials due to its dual halogen reactivity.

Safety and Hazards

GHS Hazard Statements

  • H302 (89.1%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H318 (87%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H319 (13%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (89.1%)
  • Skin Irrit. 2 (100%)
  • Eye Dam. 1 (87%)
  • Eye Irrit. 2 (13%)
  • STOT SE 3 (97.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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