Description

Guanine (CAS 73-40-5) is a naturally occurring purine derivative and one of the four nucleobases essential for DNA and RNA structure. With the molecular formula C₅H₅N₅O, it forms hydrogen bonds with cytosine in nucleic acids, playing a critical role in genetic coding and cellular processes. This high-purity compound is widely utilized in molecular biology, pharmaceutical research, and cosmetic applications due to its iridescent properties (e.g., pearl essence). Available as a fine white powder, our Guanine meets stringent quality standards, including USP and EP specifications, ensuring reliability for analytical, diagnostic, and industrial applications.

• CAS: 73-40-5
• Molecular Formula: C₅H₅N₅O
• Synonyms: 2-Amino-6-hydroxypurine, Pearl essence, CI 75170
• Purity: ≥98% (HPLC)
• Storage: Store at 2-8°C in a dry environment

Properties

• CAS Number: 73-40-5
• Complexity: 225
• IUPAC Name: 2-amino-1,7-dihydropurin-6-one
• InChI: InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• InChI Key: UYTPUPDQBNUYGX-UHFFFAOYSA-N
• Exact Mass: 151.04940980
• Molecular Formula: C5H5N5O
• Molecular Weight: 151.13
• SMILES: C1=NC2=C(N1)C(=O)NC(=N2)N
• Topological: 96.2
• Monoisotopic Mass: 151.04940980
• Physical Description: Solid; White crystals;
• Color/Form: SEVERAL DESMOTROPIC FORMS; USUALLY AMORPHOUS
• Boiling Point: BOILING POINT: SUBLIMES
• Stability/Shelf Life: DECOMP ABOVE 360 °C WITH PARTIAL SUBLIMATION
• Dissociation Constants: B: 6.09X10-4; A: 1.19X10-10 @ 40 °C
• Synonyms: guanine, 73-40-5, 2-Amino-6-hydroxypurine, Guanin, 2-Aminohypoxanthine, Mearlmaid, Guanine enol, Pearl essence, Stella Polaris, Dew Pearl, Natural white 1, Natural pearl essence, 6H-Purin-6-one, 2-amino-1,7-dihydro-, 2-Amino-6-purinol, CI Natural white 1, C.I. Natural White 1, Hypoxanthine, 2-amino-, 6-Hydroxy-2-aminopurine, 2-amino-1,9-dihydro-6H-purin-6-one, 2-Amino-1,7-dihydro-6H-purin-6-one, CI 75170, C.I. 75170, HSDB 2127, 2-amino-6-oxopurine, AI3-24393, CHEBI:16235, EINECS 200-799-8, UNII-5Z93L87A1R, 5Z93L87A1R, C.i. no. 75170 (guanine), GUA, DTXSID9052476, GUANINE (USP-RS), GUANINE [USP-RS], GUANINE (EP IMPURITY), GUANINE [EP IMPURITY], GUANINE (USP IMPURITY), GUANINE [USP IMPURITY], ACICLOVIR IMPURITY B (EP IMPURITY), ACICLOVIR IMPURITY B [EP IMPURITY], GANCICLOVIR IMPURITY F (EP IMPURITY), GANCICLOVIR IMPURITY F [EP IMPURITY], VALACICLOVIR HYDROCHLORIDE IMPURITY A (EP IMPURITY), VALACICLOVIR HYDROCHLORIDE IMPURITY A [EP IMPURITY], VALGANCICLOVIR HYDROCHLORIDE IMPURITY B (USP IMPURITY), VALGANCICLOVIR HYDROCHLORIDE IMPURITY B [USP IMPURITY], VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY A (EP IMPURITY), VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY A [EP IMPURITY], ACICLOVIR IMPURITY B, DTXCID6031049, 200-799-8, gni, 2-amino-1H-purin-6(7H)-one, 2-amino-9H-purin-6-ol, 2-amino-1,7-dihydropurin-6-one, Mearlmaid AA, 6H-Purin-6-one, 2-amino-1,9-dihydro-, MFCD00071533, 2-Amino-6-hydroxy-1H-purine, CHEMBL219568, 66224-64-4, 2-Amino-1,9-dihydro-purin-6-one, 2-amino-6,9-dihydro-1H-purin-6-one, 71660-36-1, 2-aminohydropurin-6-one, 2-Amino-1,7-dihydro-6H-purin-6-one (Guanine), GUN, 2-amino-6-hydroxypurin, 2-AMINO-3H-PURIN-6(7H)-ONE, Guanie, 6H-purin-6-one, 2-amino-3,7-dihydro-, 9h-guanine, 2-amino-1,9-dihydropurin-6-one, Guanine, BioUltra, Guanine (Standard), Guanine (8CI), 2-amino-6-oxypurin, 2-amino-Hypoxanthine, Guanine, 98%, GUANINE [HSDB], GUANINE [MI], GUANINE [WHO-IP], bmse000090, Epitope ID:140098, SCHEMBL5259, SCHEMBL5260, Oprea1_875298, purine, 2-amino-6-hydroxy-, SCHEMBL122461, SCHEMBL142922, SCHEMBL342789, SCHEMBL443984, SCHEMBL534997, SCHEMBL535022, SCHEMBL536760, GTPL4556, SCHEMBL1338837, SCHEMBL1338839, SCHEMBL2216795, SCHEMBL3241710, SCHEMBL6126257, SCHEMBL7857549, 2-amino-1h-purin-6(9h)-one, SCHEMBL10332674, SCHEMBL11877187, SCHEMBL16389311, HY-Y1055R, MSK6919, ALBB-025935, BCP26793, HY-Y1055, Valacyclovir hydrochloride, guanine-, BBL009290, BBL009641, BDBM50200094, s4888, SBB004065, STK297804, STK801924, ACICLOVIR IMPURITY B [WHO-IP], AKOS000118904, AKOS001426592, AKOS005139176, AKOS016002094, Valganciclovir hydrochloride impurity b, AC-4743, CS-6269, DB02377, FG02963, 2-amino-3,7-dihydro-6H-purin-6-one, 2-amino-6,7-dihydro-1H-purin-6-one, 2-amino-6,7-dihydro-3H-purin-6-one, NCGC00246975-01, AS-10918, NCI60_012450, ST098642, DB-015937, G0169, NS00004031, A15593, A15778, C00242, 6H-Purin-6-one, 2-amino-1,7-dihydro- (9CI), Q169313, 2-AMINO-1,7-DIHYDRO-6H-PURIN-6-ONE [WHO-IP], F8880-3425, Z256709612, 2-Amino-1,7-dihydro-6H-purin-6-one; 2-Aminohypoxanthine, 3D215030-CD54-4835-A5F4-F00F86B90978, Guanine, United States Pharmacopeia (USP) Reference Standard, Guanine, Pharmaceutical Secondary Standard; Certified Reference Material, 2-Amino-6-hydroxypurine;2-Aminohypoxanthine;2-Amino-1,7-dihydro-6H-purin-6-one, InChI=1/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11

Guanine is primarily used as a building block in nucleic acid synthesis and as a reference standard in pharmaceutical impurity testing. It serves as a key component in cosmetic formulations for its light-reflective properties, mimicking pearl-like effects. Researchers also employ Guanine in studies of genetic disorders, nucleotide metabolism, and antiviral drug development (e.g., as an impurity marker for acyclovir).

Safety and Hazards

GHS Hazard Statements

• H315 (98.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (93%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (98.3%)
• Eye Irrit. 2 (98.3%)
• STOT SE 3 (93%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.