Description

3-Bromopyridine-4-carboxaldehyde (CAS No. 70201-43-3) is a high-purity heterocyclic organic compound with the molecular formula C₆H₄BrNO. This versatile aldehyde derivative of bromopyridine is widely utilized in pharmaceutical synthesis, agrochemical research, and material science applications. The compound features a reactive aldehyde group adjacent to a bromine-substituted pyridine ring, making it a valuable bifunctional building block for cross-coupling reactions, nucleophilic additions, and heterocyclic expansions.

Our product is rigorously tested to ensure >98% purity (HPLC) and is supplied as a crystalline solid with typical lot impurities including less than 0.5% residual solvents. The material is packaged under inert atmosphere in amber glass vials to ensure stability and is suitable for use in sensitive organometallic reactions. Technical specifications include: molecular weight 186.01 g/mol, melting point 85-88°C, and storage recommendations of 2-8°C under nitrogen.

Properties

• CAS Number: 70201-43-3
• Complexity: 107
• IUPAC Name: 3-bromopyridine-4-carbaldehyde
• InChI: InChI=1S/C6H4BrNO/c7-6-3-8-2-1-5(6)4-9/h1-4H
• InChI Key: NOBDKWLIAQKADB-UHFFFAOYSA-N
• Exact Mass: 184.94763
• Molecular Formula: C6H4BrNO
• Molecular Weight: 186.01
• SMILES: C1=CN=CC(=C1C=O)Br
• Topological: 30
• Monoisotopic Mass: 184.94763
• Synonyms: 3-Bromopyridine-4-carboxaldehyde, 627-770-6, 70201-43-3, 3-Bromo-4-pyridinecarboxaldehyde, 3-bromoisonicotinaldehyde, 3-bromopyridine-4-carbaldehyde, 3-BROMO-4-FORMYLPYRIDINE, MFCD05864506, 3-BROMO-4-PYRIDINECARBALDEHYDE, 4-PYRIDINECARBOXALDEHYDE, 3-BROMO-, bromoisonicotinaldehyde, SCHEMBL526587, 3-bromo-4-pyridine carbaldehyde, 3-bromo-pyridine-4-carbaldehyde, 5-bromo-pyridine-4-carbaldehyde, 5-Bromopyridine-4-carboxaldehyde, DTXSID70376648, 3-bromo-pyridine-4-carboxaldehyde, NOBDKWLIAQKADB-UHFFFAOYSA-N, BCP23221, BBL101422, CL8878, GEO-03429, SBB052233, STL555218, AKOS005258084, AC-4389, CS-W007984, PB17335, PS-5690, 3-Bromo-4-pyridinecarboxaldehyde, 97%, SY005098, DB-011158, B2624, EN300-76949, A25710, 3-Bromo-4-formylpyridine;3-Bromoisonicotinaldehyde, Z1192338771, 3-Bromopyridine-4-carboxaldehyde;3-Bromoisonicotinaldehyde;3-Bromopyridine-4-carboxaldehyde, 3-Bromo-4-formylpyridine; 3-Bromoisonicotinaldehyde; 3-Bromopyridine-4-carbaldehyde; 5-Bromopyridine-4-carboxaldehyde

Application

3-Bromopyridine-4-carboxaldehyde serves as a key intermediate in the synthesis of novel pharmaceutical compounds, particularly in the development of kinase inhibitors and antiviral agents. The compound’s dual functionality enables efficient construction of complex heterocyclic systems through Suzuki-Miyaura coupling or reductive amination pathways. Researchers frequently employ this building block in medicinal chemistry for structure-activity relationship studies due to its ability to introduce both halogen and aldehyde handles for further derivatization.

Safety and Hazards

GHS Hazard Statements

• H302 (93.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (91.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (11.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (93.3%)
• Skin Irrit. 2 (100%)
• Skin Sens. 1 (91.1%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (11.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.