Description

Hypoxanthine (CAS 68-94-0) is a naturally occurring purine derivative with the molecular formula C₅H₄N₄O. It serves as a key intermediate in nucleotide metabolism and is essential for biochemical research, pharmaceutical development, and cell culture applications. This high-purity compound is widely utilized in studies involving nucleic acid synthesis, enzyme kinetics, and metabolic pathways. Available as a fine white powder, our Hypoxanthine meets stringent quality standards, ensuring optimal performance in experimental and industrial settings.

Key Features:

• High Purity: ≥99% (HPLC)
• Molecular Weight: 136.11 g/mol
• Melting Point: 150-152°C (dec.)
• Solubility: Soluble in dilute acids and alkalis; slightly soluble in water
• Storage: Store at 2-8°C in a dry environment

Ideal for researchers in enzymology, molecular biology, and drug discovery, this product is rigorously tested for consistency and reliability.

Properties

• CAS Number: 68-94-0
• Complexity: 190
• IUPAC Name: 1,7-dihydropurin-6-one
• InChI: InChI=1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
• InChI Key: FDGQSTZJBFJUBT-UHFFFAOYSA-N
• Exact Mass: 136.03851076
• Molecular Formula: C5H4N4O
• Molecular Weight: 136.11
• SMILES: C1=NC2=C(N1)C(=O)NC=N2
• Topological: 70.1
• Monoisotopic Mass: 136.03851076
• Physical Description: Solid; White powder;
• Synonyms: hypoxanthine, 68-94-0, 6-Hydroxypurine, 9H-Purin-6-ol, 7H-Purin-6-ol, 3H-Purin-6-ol, Sarkin, 6-Oxopurine, Sarcine, 1,7-Dihydro-6H-purin-6-one, Purin-6(1H)-one, Sarkine, Purin-6-ol, Hypoxanthine enol, 6(1H)-Purinone, 9H-Purin-6(1H)-one, Purin-6(3H)-one, 6-Hydroxy-1H-purine, 6H-Purin-6-one, 1,7-dihydro-, Purine-6-ol, 1,7-Dihydro-6H-purine-6-one, 9H-Purin-6-ol (VAN), 6H-Purin-6-one, 1,9-dihydro-, 6,7-dihydro-3H-purin-6-one, Hypoxanthine (VAN), NSC 14665, CHEBI:17368, AI3-52242, EINECS 200-697-3, DIDANOSINE IMPURITY A, 1H,7H-Hypoxanthine, DTXSID8045983, 4-Hydroxy-1H-purine, 2TN51YD919, HYPOXANTHINE [MI], NSC-14665, NSC 129419, Hypoxanthine (VAN) (8CI), HYPOXANTHINE [WHO-DD], DTXCID6025983, NSC14665, DIDANOSINE IMPURITY A [EP IMPURITY], AZATHIOPRINE IMPURITY F [EP IMPURITY], DIDANOSINE IMPURITY A (EP IMPURITY), AZATHIOPRINE IMPURITY F (EP IMPURITY), MERCAPTOPURINE IMPURITY, HYPOXANTHINE-(EP IMPURITY), MERCAPTOPURINE IMPURITY, HYPOXANTHINE-(USP IMPURITY), MERCAPTOPURINE IMPURITY, HYPOXANTHINE-[EP IMPURITY], MERCAPTOPURINE IMPURITY, HYPOXANTHINE-[USP IMPURITY], 6Hydroxypurine, 6oxopurine, Purin6ol, 6Hydroxy1Hpurine, 3HPurin6ol, 9HPurin6ol, 6(1H)Purinone, Purin6(1H)one, Purin6(3H)one, 9HPurin6(1H)one, 1,7Dihydro6Hpurin6one, 6HPurin6one, 1,7dihydro, 6HPurin6one, 1,9dihydro, 200-697-3, inchi=1/c5h4n4o/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2h,(h2,6,7,8,9,10, 1h-purin-6-ol, 3,7-dihydropurin-6-one, 1,9-dihydro-6H-purin-6-one, 146469-94-5, 95121-06-5, 1H-Purin-6-ol (9CI), 51953-04-9, 146445-70-7, 146469-95-6, MFCD00005725, 6H-Purin-6-one, 3,7-dihydro- (9CI), HX, CHEMBL1427, 6,7-dihydro-1H-purin-6-one, NCGC00095622-01, 1246820-04-1, 1,7-Dihydro-6H-purin-6-one (Hypoxanthine), Discontinued. See H998503 or H998504, 1H-Purin-6(9H)-one, F1386-0269, CAS-68-94-0, 146469-96-7, purin-6(1H)-on, UNII-2TN51YD919, 3h-hypoxanthine, 6-hydroxypurin, 6-purinol, 1vfn, 3nrz, Sarcine;Purin-6-ol, purine, 6-hydroxy-, Spectrum_001417, 1a9q, Hypoxanthine (Standard), 7H-Purin-6-ol #, SpecPlus_000461, Spectrum2_001907, Spectrum3_001352, Spectrum4_001742, Spectrum5_000564, 1,9-dihydropurin-6-one, 3H-Purin-6(9H)-one, bmse000094, Epitope ID:167471, 1,9-Dihydro-purin-6-one, Hypoxanthine, >=99.0%, SCHEMBL25381, SCHEMBL25382, SCHEMBL25383, BSPBio_003163, KBioGR_002184, KBioSS_001897, SPECTRUM310023, 51953-23-2, DivK1c_006557, Mercaptopurine impurity A CRS, SCHEMBL158472, SCHEMBL158473, SCHEMBL275944, SCHEMBL275945, SCHEMBL355917, SCHEMBL440223, SCHEMBL446722, SCHEMBL822613, SPBio_001874, GTPL4555, SCHEMBL1867923, SCHEMBL3245216, SCHEMBL3696833, SCHEMBL4361878, SCHEMBL8012415, SCHEMBL8079826, SCHEMBL8169178, SCHEMBL9043222, SCHEMBL9047405, SCHEMBL14793560, SCHEMBL17276814, SCHEMBL21332344, BDBM82018, FDGQSTZJBFJUBT-UHFFFAOYSA-, HY-N0091R, KBio1_001501, KBio2_001897, KBio2_004465, KBio2_007033, KBio3_002383, CAS_790, MSK6923, NSC_790, HMS5087P17, 6H-Purin-6-one, 3,7-dihydro-, 6H-Purin-6-one, 3,9-dihydro-, SMSSF-0040850, BCP22929, FDC26504, HY-N0091, Tox21_111511, CCG-38478, PDSP1_000299, PDSP2_000297, s2424, SBB004203, STK804424, AKOS000267572, AKOS005221762, AKOS009159101, AKOS015888571, AKOS022168213, Tox21_111511_1, 6-Hydroxypurine; Purin-6-ol; Sarcine, DB04076, FH02949, PS-3167, SDCCGMLS-0065594.P001, SDCCGMLS-0065594.P002, NCGC00095622-04, AC-10518, AC-32451, SY012477, DB-029904, DB-264101, DB-273114, DB-273118, DB-273292, DB-325530, CS-0007792, H0311, NS00010150, ST50160486, SW219908-1, 1,9-Dihydro-6H-purin-6-one;6-Hydroxypurine, EN300-37579, Hypoxanthine, Vetec(TM) reagent grade, 98%, Hypoxsanthine (1,7-Dihydro-6H-purin-6-one), C00262, Hypoxanthine, Low endotoxin: <= 0.04 EU/mg, AB00674258-01, AC-907/21098001, AG-670/31547063, Q410305, SR-05000002375, SR-05000002375-1, BRD-K03739921-001-06-8, Z1954805546, Hypoxanthine, powder, BioReagent, suitable for cell culture, MERCAPTOPURINE IMPURITY, HYPOXANTHINE- [EP IMPURITY], 8C229956-6BE8-4F8D-91B7-0AD1EC294077, MERCAPTOPURINE IMPURITY, HYPOXANTHINE- [USP IMPURITY], Didanosine impurity A,, European Pharmacopoeia (EP) Reference Standard, InChI=1/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

Hypoxanthine is primarily used as a precursor in the synthesis of purine nucleotides and as a substrate for xanthine oxidase studies. It plays a critical role in cell culture media formulations, particularly for hybridoma and lymphocyte cultures. Additionally, it serves as a biomarker in clinical diagnostics for conditions like gout and Lesch-Nyhan syndrome. Its applications extend to pharmaceutical impurity testing and metabolic pathway research.

Safety and Hazards

GHS Hazard Statements

• H315 (40%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (40%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (40%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (40%)
• Eye Irrit. 2 (40%)
• STOT SE 3 (40%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.