Description

Cytidine (CAS No. 65-46-3) is a nucleoside composed of the pyrimidine base cytosine attached to a ribose sugar moiety via a β-N₁-glycosidic bond. This white crystalline powder is highly soluble in water and serves as a fundamental building block in RNA synthesis, playing a critical role in genetic coding and cellular metabolism. With a molecular formula of C₉H₁₃N₃O₅, cytidine is widely utilized in molecular biology research, pharmaceutical development, and diagnostic applications. Our high-purity cytidine (≥99% by HPLC) is rigorously tested for contaminants, ensuring optimal performance in enzymatic assays, cell culture media, and nucleotide analog synthesis. Each batch is supplied with comprehensive analytical documentation, including NMR and mass spectrometry data, to meet the stringent requirements of academic and industrial researchers.

Properties

• CAS Number: 65-46-3
• Complexity: 383
• IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
• InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
• InChI Key: UHDGCWIWMRVCDJ-XVFCMESISA-N
• LogP: -2.51
• Exact Mass: 243.08552052
• Molecular Formula: C9H13N3O5
• Molecular Weight: 243.22
• SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
• Topological: 129
• Monoisotopic Mass: 243.08552052
• Physical Description: Cytidine is a white crystalline powder.
• Melting Point: 419 to 421 °F
• Solubility: greater than or equal to 100 mg/mL at 63 °F
• Vapor Pressure: Negligible
• Synonyms: cytidine, 65-46-3, Cytosine riboside, 1-beta-D-Ribofuranosylcytosine, 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone, 1beta-Ribofuranosylcytosine, Zytidin, 1-beta-Ribofuranosylcytosine, beta-D-Ribofuranoside, cytosine-1, 1beta-D-Ribofuranosylcytosine, 4-Amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone, Cytosine, 1-beta-D-ribofuranosyl-, 1beta-2′-Ribofuranosylcytosine, d-, NSC 20258, cytosine-1beta-D-Ribofuranoside, CHEBI:17562, EINECS 200-610-9, 2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl-, Posilent (TN), 5CSZ8459RP, 2(1H)-Pyrimidinone, 4-amino-1beta-D-ribofuranosyl-, CYTIDINE [MI], 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, NSC-20258, CYTIDINE [MART.], CYTIDINE [WHO-DD], 4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one, 1.beta.-Ribofuranosylcytosine, 1.beta.-D-Ribofuranosylcytosine, DTXSID60891552, .beta.-D-Ribofuranoside, cytosine-1, MMV638723, Cytosine, 1-.beta.-D-ribofuranosyl-, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one, CYTIDINE (MART.), 4-Amino-1.beta.-D-ribofuranosyl-2(1H)-pyrimidinone, 2(1H)-Pyrimidinone, 4-amino-1-.beta.-D-ribofuranosyl-, Riboside, Cytosine, Cytosine Ribonucleoside, Ribonucleoside, Cytosine, Posilent, 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2-dihydropyrimidin-2-one, CYTIDINE [INCI], 1betaRibofuranosylcytosine, 1betaDRibofuranosylcytosine, Cytosine, 1betaDribofuranosyl, betaDRibofuranoside, cytosine1, 1beta2’Ribofuranosylcytosine, d, 1-BETA-RIBOFURANOSYLOSINE, DTXCID901030645, CYTOSINE, 1-BETA-D-RIBOSYL-, 4Amino1betaDribofuranosyl2(1H)pyrimidinone, 2(1H)Pyrimidinone, 4amino1betaDribofuranosyl, 200-610-9, uhdgcwiwmrvcdj-xvfcmesisa-n, Cytidin, Cyd, MFCD00006545, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one, C9H13N3O5, 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one, Cytidine; Cytarabine Impurity E, CTN, SMR000058243, UNII-5CSZ8459RP, beta-cytidine, 3h-cytidine, beta.-D-Ribo-C, Cytidine, 99%, 1-b-D-ribosyl-Cytosine, Cytosine beta-D-riboside, Cytosine-beta-D-riboside, CP-C, bmse000190, bmse000969, bmse001020, Epitope ID:141494, SCHEMBL7179, 1-b-D-Ribofuranosylcytosine, cytosine-1b-D-Ribofuranoside, beta-D-ribofuranosyl-cytidine, MLS000049947, MLS002207040, 1-beta-D-ribosyl- (6CI), 1-beta-delta-ribosyl-Cytosine, CHEMBL95606, GTPL4728, SCHEMBL8525830, 1-beta-D-ribofuranosyl-Cytosine, cytosine-1b-delta-Ribofuranoside, SCHEMBL17856892, SCHEMBL24781031, 1beta-delta-Ribofuranosylcytosine, Cytosine-1-beta-D-ribofuranoside, MSK6801, 1-beta-delta-Ribofuranosylcytosine, Cytidine, >=99.0% (HPLC), cytosine-1beta-delta-Ribofuranoside, 1-beta-delta-ribofuranosyl-Cytosine, HY-B0158, s2053, SBB003195, AKOS015888568, CCG-266896, CS-1989, DB02097, NC04070, SRI-2352_17, NCGC00093356-08, NCGC00142483-01, NCGC00142483-09, AS-12696, BP-58628, ST056938, DB-029614, NS00069068, C00475, D07769, EN300-184125, 1-(beta-D-ribofuranosyl)-4-aminopyrimidin-2-one, 4-Amino-1-|A-D-ribofuranosyl-2(1H)-pyrimidinone, 4-Amino-1-b-D-ribofuranosyl-2(1H)-pyrimidinone, Cytosine -D-riboside;Cytosine-1–D-ribofuranoside, Q422538, BRD-K71847383-001-07-5, BRD-K71847383-001-12-5, 4-Amino-1-.beta.-D-ribofuranosyl-2-(1H)-pyrimidinone, 4-Amino-1-beta-delta-ribofuranosyl-2(1H)-pyrimidinone, F0348-2240, Z1879263740, 1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine, 6D2DC474-DD76-4081-8B34-10605C218F49, 1-(b-delta-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine, 1-(beta-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine, Cytidine, BioReagent, suitable for cell culture, powder, >=99%

Cytidine is essential for studying RNA structure and function, serving as a precursor for mRNA and tRNA synthesis. It is used in cell culture media to support nucleotide metabolism in proliferating cells. Researchers also employ cytidine derivatives to investigate epigenetic modifications, such as DNA methylation, and to develop antiviral or anticancer therapeutics targeting nucleic acid pathways.

Safety and Hazards

GHS Hazard Statements

• H315 (16.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (16.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (16.7%)
• Eye Irrit. 2A (16.7%)
• STOT SE 3 (16.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.