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Atomfair 2-Chloro-3-hydrazinopyrazine C4H5ClN4 CAS 63286-28-2

2-Chloro-3-hydrazinopyrazine (CAS No. 63286-28-2) is a high-purity heterocyclic compound with the molecular formula C4H5ClN4and IUPAC name (3-chloropyrazin-2-yl)hydrazine . This specialized chemical is a valuable building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and functional materials. Its reactive hydrazine and chloro substituents on the pyrazine ring enable diverse derivatization, making it ideal for nucleophilic substitution, condensation, and cyclization reactions. Our product is rigorously tested to ensure ≥95% purity (HPLC) and is supplied as a crystalline solid with full analytical documentation (MS, NMR, FTIR). Suitable for research-scale and process development applications, it is packaged under inert gas to…

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Description

2-Chloro-3-hydrazinopyrazine (CAS No. 63286-28-2) is a high-purity heterocyclic compound with the molecular formula C4H5ClN4 and IUPAC name (3-chloropyrazin-2-yl)hydrazine. This specialized chemical is a valuable building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and functional materials. Its reactive hydrazine and chloro substituents on the pyrazine ring enable diverse derivatization, making it ideal for nucleophilic substitution, condensation, and cyclization reactions. Our product is rigorously tested to ensure ≥95% purity (HPLC) and is supplied as a crystalline solid with full analytical documentation (MS, NMR, FTIR). Suitable for research-scale and process development applications, it is packaged under inert gas to ensure stability and shipped with proper handling precautions.

Properties

  • CAS Number: 63286-28-2
  • Complexity: 88.6
  • IUPAC Name: (3-chloropyrazin-2-yl)hydrazine
  • InChI: InChI=1S/C4H5ClN4/c5-3-4(9-6)8-2-1-7-3/h1-2H,6H2,(H,8,9)
  • InChI Key: PUUGNIKJWZNTBK-UHFFFAOYSA-N
  • Exact Mass: 144.0202739
  • Molecular Formula: C4H5ClN4
  • Molecular Weight: 144.56
  • SMILES: C1=CN=C(C(=N1)NN)Cl
  • Topological: 63.8
  • Monoisotopic Mass: 144.0202739
  • Synonyms: 2-Chloro-3-hydrazinopyrazine, 640-727-6, 2-chloro-3-hydrazinylpyrazine, 63286-28-2, (3-chloropyrazin-2-yl)hydrazine, 1-(3-chloropyrazin-2-yl)hydrazine, MFCD08272804, 2-(3-CHLOROPYRAZIN-2-YL)HYDRAZINE, 3-Chloro-2(H)-pyrazinone hydrazone, NSC272203, 2(1H)-PYRAZINONE, 3-CHLORO-, HYDRAZONE, 3-chloro-2-hydrazinopyrazine, 2-chloro-3-hydrazineylpyrazine, SCHEMBL1179963, OSM-S-657, DTXSID00313546, 2-Chloro-3-hydrazinopyrazine, 95%, BBL005540, GEO-03685, STL134905, AKOS005745086, CS-W011003, NSC-272203, PB16012, PS-5656, SY031007, EN300-75567, (3-Chloro-pyrazin-2-yl)-hydrazine; hydrochloride

Application

2-Chloro-3-hydrazinopyrazine serves as a key intermediate in medicinal chemistry for synthesizing pyrazine-based drug candidates, particularly kinase inhibitors and antimicrobial agents. Its reactive sites facilitate the construction of fused heterocycles like pyrazolo[1,5-a]pyrazines, valuable scaffolds in drug discovery. The compound is also employed in coordination chemistry for ligand design and in material science for functionalized polymer synthesis.

Safety and Hazards

GHS Hazard Statements

  • H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H318 (95.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 3 (97.6%)
  • Skin Irrit. 2 (100%)
  • Eye Dam. 1 (95.1%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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