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Atomfair 2-Chloro-3-pyridylamine C5H5ClN2 CAS 6298-19-7

2-Chloro-3-pyridylamine (CAS No. 6298-19-7) is a high-purity organic compound with the molecular formula C5H5ClN2, widely utilized in pharmaceutical and agrochemical research. This compound, also known by its IUPAC name 2-chloropyridin-3-amine , features a chlorinated pyridine ring with an amine group at the 3-position, making it a versatile intermediate for heterocyclic synthesis. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC) and is supplied as a fine crystalline powder with excellent solubility in common organic solvents like DMSO, ethanol, and dichloromethane. Ideal for cross-coupling reactions, functional group transformations, and as a precursor for bioactive molecules, this compound is packaged under…

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Description

2-Chloro-3-pyridylamine (CAS No. 6298-19-7) is a high-purity organic compound with the molecular formula C5H5ClN2, widely utilized in pharmaceutical and agrochemical research. This compound, also known by its IUPAC name 2-chloropyridin-3-amine, features a chlorinated pyridine ring with an amine group at the 3-position, making it a versatile intermediate for heterocyclic synthesis. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC) and is supplied as a fine crystalline powder with excellent solubility in common organic solvents like DMSO, ethanol, and dichloromethane. Ideal for cross-coupling reactions, functional group transformations, and as a precursor for bioactive molecules, this compound is packaged under inert conditions to guarantee stability and longevity. Each batch is accompanied by comprehensive analytical data, including 1H NMR, 13C NMR, and mass spectrometry reports.

Properties

  • CAS Number: 6298-19-7
  • Complexity: 76.8
  • IUPAC Name: 2-chloropyridin-3-amine
  • InChI: InChI=1S/C5H5ClN2/c6-5-4(7)2-1-3-8-5/h1-3H,7H2
  • InChI Key: MEQBJJUWDCYIAB-UHFFFAOYSA-N
  • Exact Mass: 128.0141259
  • Molecular Formula: C5H5ClN2
  • Molecular Weight: 128.56
  • SMILES: C1=CC(=C(N=C1)Cl)N
  • Topological: 38.9
  • Monoisotopic Mass: 128.0141259
  • Synonyms: 3-Amino-2-chloropyridine, 6298-19-7, 2-Chloro-3-aminopyridine, 3-Pyridinamine, 2-chloro-, 2-Chloro-3-pyridylamine, 2-chloropyridin-3-ylamine, WFH374WQE6, EINECS 228-572-9, NSC-45407, 2-CHLORO-3-PYRIDINEAMINE, DTXSID40212185, NSC 45407, DTXCID40134676, 228-572-9, 2-chloropyridin-3-amine, 2-Chloro-3-pyridinamine, MFCD00006238, 2-chloro-pyridin-3-ylamine, Pyridine, 3-amino-2-chloro-, 3-amino-2-chloro-pyridine, 2-Chloranylpyridin-3-Amine, Pyridine, 2-chloro-3-amino-, 2-CHLORO-3-PYRIDINYLAMINE, 2-Chloro-3-amino-pyridine, NSC45407, 2chloro-3-aminopyridine, UNII-WFH374WQE6, SCHEMBL160353, SCHEMBL2067997, SCHEMBL3516919, SCHEMBL4051565, SCHEMBL6543714, CHEMBL4639717, 3-Amino-2-chloropyridine, 98%, BCP26985, HY-Y0244, SBB004233, STK506778, AKOS000119691, AC-4662, CS-W019980, PB23167, PS-5762, SB21670, BP-21331, SY005474, DB-022191, DB-239897, A0836, NS00035236, ST50325039, EN300-19839, P16534, AC-907/25014052, SR-01000944743, SR-01000944743-1, F3284-8126, Z104475710, InChI=1/C5H5ClN2/c6-5-4(7)2-1-3-8-5/h1-3H,7H, L97

Application

2-Chloro-3-pyridylamine serves as a key building block in the synthesis of pharmaceuticals, particularly for antimalarial and antiviral agents. It is also employed in the development of herbicides and insecticides due to its pyridine-based scaffold. Researchers utilize this compound in Pd-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex heterocycles. Its amine group allows for further derivatization, enabling the creation of sulfonamides, ureas, or amides for drug discovery pipelines.

Safety and Hazards

GHS Hazard Statements

  • H315 (86.5%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (86.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (84.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (86.5%)
  • Eye Irrit. 2 (86.5%)
  • STOT SE 3 (84.6%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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