Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 2-(3-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane C15H21BO2 CAS 627526-56-1

2-(3-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS No. 627526-56-1) is a high-purity boronic ester compound with the molecular formula C15H21BO2. This organoboron reagent is widely utilized in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic organic chemistry. The compound features a cyclopropylphenyl moiety tethered to a pinacol boronate ester group, offering enhanced stability and reactivity compared to boronic acids. With a molecular weight of 244.14 g/mol, this white to off-white crystalline solid is meticulously synthesized and purified to meet the stringent requirements of pharmaceutical research, materials science, and advanced chemical synthesis. Suitable for use under inert atmospheres, it is packaged in amber glass vials…

Category:

Description

2-(3-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS No. 627526-56-1) is a high-purity boronic ester compound with the molecular formula C15H21BO2. This organoboron reagent is widely utilized in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic organic chemistry. The compound features a cyclopropylphenyl moiety tethered to a pinacol boronate ester group, offering enhanced stability and reactivity compared to boronic acids. With a molecular weight of 244.14 g/mol, this white to off-white crystalline solid is meticulously synthesized and purified to meet the stringent requirements of pharmaceutical research, materials science, and advanced chemical synthesis. Suitable for use under inert atmospheres, it is packaged in amber glass vials to ensure long-term stability. Purity is typically ≥95% by HPLC analysis.

Properties

  • CAS Number: 627526-56-1
  • Complexity: 306
  • IUPAC Name: 2-(3-cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • InChI: InChI=1S/C15H21BO2/c1-14(2)15(3,4)18-16(17-14)13-7-5-6-12(10-13)11-8-9-11/h5-7,10-11H,8-9H2,1-4H3
  • InChI Key: VHNQNDFTCALSPV-UHFFFAOYSA-N
  • Exact Mass: 244.1634601
  • Molecular Formula: C15H21BO2
  • Molecular Weight: 244.14
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)C3CC3
  • Topological: 18.5
  • Monoisotopic Mass: 244.1634601
  • Synonyms: 627526-56-1, 2-(3-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, DTXSID20623715, DTXCID10574469, 961-441-0, 2-(3-CYCLOPROPYLPHENYL)-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE, MFCD08061969, 1,3,2-Dioxaborolane, 2-(3-cyclopropylphenyl)-4,4,5,5-tetramethyl-, (3-CYCLOPROPYLPHENYL)BORONIC ACID PINACOL ESTER, SCHEMBL1821378, VHNQNDFTCALSPV-UHFFFAOYSA-N, CAB52656, AKOS005259000, AB43369, DS-18286, SY105604, DB-073186, CS-0153844, 3-Cyclopropylphenylboronic Acid Pinacol Ester, Cyclopropylphenyl-3-boronic acid pinacol ester, EN300-705479, N10508, 3-(Cyclopropyl) phenyl boronic acid pinacol ester, Z2044776603, 2-(3-cyclopropyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Application

This boronic ester is principally employed as a key intermediate in palladium-catalyzed cross-coupling reactions for constructing biaryl systems prevalent in drug discovery. Its cyclopropyl group confers unique steric and electronic properties to resultant compounds, making it valuable for developing bioactive molecules. Researchers utilize it in synthesizing advanced materials with tailored optoelectronic characteristics. The compound’s stability allows for convenient handling in multi-step synthetic sequences.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products