Description

L-Homocystine (CAS 626-72-2) is a high-purity sulfur-containing amino acid dimer widely used in biochemical research and pharmaceutical applications. With the molecular formula C₈H₁₆N₂O₄S₂, this compound is an oxidized form of homocysteine, featuring a disulfide bridge critical for studying redox biology, metabolic pathways, and neurodegenerative disorders. Our product is available in >=98% purity (HPLC), ensuring reliability for cell culture studies, enzymatic assays, and biomarker research. It is cell culture tested, making it ideal for in vitro experiments requiring stringent quality standards. Packaged under inert conditions to preserve stability, L-Homocystine is a key reagent for investigating homocysteine metabolism, cardiovascular disease mechanisms, and oxidative stress responses.

Properties

• CAS Number: 626-72-2
• Complexity: 216
• IUPAC Name: (2S)-2-amino-4-[[(3S)-3-amino-3-carboxy-propyl]disulfanyl]butanoic acid
• InChI: InChI=1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6-/m0/s1
• InChI Key: ZTVZLYBCZNMWCF-WDSKDSINSA-N
• Exact Mass: 268.05514934
• Molecular Formula: C8H16N2O4S2
• Molecular Weight: 268.4
• SMILES: C(CSSCC[C@@H](C(=O)O)N)[C@@H](C(=O)O)N
• Topological: 177
• Monoisotopic Mass: 268.05514934
• Synonyms: L-Homocystine, 626-72-2, Homocystine, L-, 804AS222UE, EINECS 210-962-5, L-HOMOCYSTINE [MI], HOMOCYSTINE, (+)-, Butanoic acid, 4,4′-dithiobis(2-amino-, (2S,2’S)-, 2-amino-4-{[(3S)-3-amino-3-carboxypropyl]disulfanyl}butanoic acid, DTXSID001019905, [S-(R*,R*)]-4,4′-dithiobis[2-aminobutyric] acid, (S-(R*,R*))-4,4′-Dithiobis(2-aminobutyric) acid, BUTYRIC ACID, 4,4′-DITHIOBIS(2-AMINO-, L-, Butanoic acid, 4,4′-dithiobis[2-amino-, (2S,2’S)-, Butanoic acid, 4,4′-dithiobis[2-amino-, [S-(R*,R*)]-, BUTANOIC ACID, 4,4′-DITHIOBIS(2-AMINO-, (S-(R*,R*))-, 2-amino-4-(((3S)-3-amino-3-carboxypropyl)disulfanyl)butanoic acid, DTXCID801477767, 210-962-5, (H-HoCys-OH)2, (2S)-2-amino-4-[[(3S)-3-amino-3-carboxypropyl]disulfanyl]butanoic acid, rel-(2S,2’S)-4,4′-Disulfanediylbis(2-aminobutanoic acid), (2S)-2-amino-4-{[(3S)-3-amino-3-carboxypropyl]disulfanyl}butanoic acid, C8H16N2O4S2, MFCD00020391, (2S,2’S)-4,4′-Disulfanediylbis(2-aminobutanoic acid), (2S,2’S)-homocystine, UNII-804AS222UE, Butanoic acid, 4,4′-dithiobis[2-amino-, [S-(R*,R*)]-; Butyric acid, 4,4′-dithiobis[2-amino-, L- (8CI); (2S,2’S)-4,4′-Dithiobis[2-aminobutanoic acid]; L-Homocystine, L-4,4′-Dithiobis(2-aminobutanoic acid), SCHEMBL385397, L-Homocystine (H-L-HCystine), MSK1474, CHEBI:141698, L-Homocystine, cell culture tested, L-Homocystine, >=98% (HPLC), AKOS015924140, CS-W012406, FH47108, HY-W011690, DS-18098, L-4,4′-dithio-bis(2-aminobutyric acid), L-Homocystine, purum, >=98.0% (NT), L-4,4′-dithio-bis(2-aminobutanoic acid), EN300-36962, C01817, (2S,2’S)-4,4′-dithiobis(2-aminobutanoic acid), (2S,2’S)-4,4′-dithiobis(2-aminobutyric acid), Q24188398, 451C7394-EBB7-4FF8-823E-43C3DCBF69BE, (H-L-HomoCys-OH)2;L-4,4′-Dithio-bis(2-aminobutanoic acid), (S)-2-amino-4-((S)-3-amino-3-carboxy-propyldisulfanyl)-butyric acid

L-Homocystine is primarily used as a reference standard in metabolomics and clinical research to study homocystinuria and hyperhomocysteinemia. It serves as a substrate for enzymes like cystathionine β-synthase (CBS) in sulfur metabolism studies. Researchers also employ it to investigate oxidative stress models and endothelial dysfunction linked to cardiovascular diseases. Its role in protein structure analysis (disulfide bond formation) makes it valuable for bioconjugation and peptide synthesis applications.

Safety and Hazards

GHS Hazard Statements

• Not Classified
• Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.

Hazard Classes and Categories

• Not Classified

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.