Description
2-(4-Nitrophenyl)acetohydrazide (CAS No. 6144-81-6) is a high-purity chemical compound with the molecular formula C8H9N3O3, widely utilized in pharmaceutical research, organic synthesis, and biochemical applications. This fine chemical exhibits excellent stability and reactivity, making it an essential intermediate for the development of novel therapeutics, agrochemicals, and specialty materials. With a molecular weight of 195.18 g/mol, it is supplied as a crystalline solid, ensuring consistent performance in demanding experimental protocols. Our product undergoes rigorous quality control, including HPLC and NMR analysis, to guarantee ≥98% purity, meeting the stringent requirements of research and industrial laboratories. Suitable for use in peptide coupling, hydrazide-based derivatization, and heterocyclic synthesis, this compound is packaged under inert conditions to preserve its integrity.
Properties
- CAS Number: 6144-81-6
- Complexity: 218
- IUPAC Name: 2-(4-nitrophenyl)acetohydrazide
- InChI: InChI=1S/C8H9N3O3/c9-10-8(12)5-6-1-3-7(4-2-6)11(13)14/h1-4H,5,9H2,(H,10,12)
- InChI Key: JFONGQRKKZPXLX-UHFFFAOYSA-N
- Exact Mass: 195.06439116
- Molecular Formula: C8H9N3O3
- Molecular Weight: 195.18
- SMILES: C1=CC(=CC=C1CC(=O)NN)[N+](=O)[O-]
- Topological: 101
- Monoisotopic Mass: 195.06439116
- Synonyms: 2-(4-nitrophenyl)acetohydrazide, 6144-81-6, 4-Nitrophenylacetic acid hydrazide, MFCD01001352, NSC147107, p-Nitrophenylacetylhydrazin, Oprea1_166973, SCHEMBL2494960, DTXSID60301888, 2-(4-nitrophenyl)acetohydrazide-, JFONGQRKKZPXLX-UHFFFAOYSA-N, ALBB-001042, BBL007939, SBB000339, STK346971, AKOS000295917, NSC-147107, ST021045, VS-01755, CS-0312827, H21215
2-(4-Nitrophenyl)acetohydrazide is extensively employed as a key intermediate in the synthesis of heterocyclic compounds and pharmaceutical agents. It serves as a versatile building block for hydrazone formation and Schiff base reactions, critical in medicinal chemistry. Researchers utilize this compound in the development of antibacterial and anticancer drug candidates due to its reactive hydrazide moiety. Its nitrophenyl group also facilitates spectrophotometric assays and labeling applications.
Safety and Hazards
GHS Hazard Statements
- H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statements
- P264, P270, P301+P317, P330, and P501
Hazard Classes and Categories
- Acute Tox. 4 (100%)
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