Description

Homocysteine thiolactone hydrochloride, DL- (CAS No. 6038-19-3) is a high-purity biochemical compound extensively utilized in research and pharmaceutical applications. This white to off-white crystalline powder, with the molecular formula C₄H₈ClNOS, is a derivative of homocysteine and serves as a critical intermediate in metabolic studies, particularly those investigating homocysteine-related disorders such as cardiovascular diseases and neurodegenerative conditions. Its thiolactone structure enables unique reactivity, making it valuable for synthesizing modified peptides, studying protein N-homocysteinylation, and exploring oxidative stress mechanisms. With ≥99.0% purity (AT), this product is rigorously tested for consistency and stability, ensuring reliable performance in sensitive assays and synthetic protocols. Packaged under inert conditions to prevent degradation, it is ideal for laboratory use in biochemistry, molecular biology, and medicinal chemistry.

Properties

• CAS Number: 6038-19-3
• Complexity: 93.7
• IUPAC Name: 3-aminotetrahydrothiophen-2-one;hydrochloride
• InChI: InChI=1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
• InChI Key: ZSEGSUBKDDEALH-UHFFFAOYSA-N
• Exact Mass: 153.0015127
• Molecular Formula: C4H8ClNOS
• Molecular Weight: 153.63
• SMILES: C1CSC(=O)C1N.Cl
• Topological: 68.4
• Monoisotopic Mass: 153.0015127
• Synonyms: 6038-19-3, DL-Homocysteine thiolactone hydrochloride, HCTL hydrochloride, D,L-Homocysteine thiolactone hydrochloride, EINECS 227-923-3, 5D8467GAGD, D,L-Homocysteinthiolakton chlorid, D,L-Homocysteinthiolakton chlorid [German], Homocysteine thiolactone hydrochloride, DL-, NSC-22879, (+-)-Dihydro-3-amino-2(3H)-thiophenone hydrochloride, 2(3H)-Thiophenone, dihydro-3-amino-, hydrochloride, (+-)-, 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride, HOMOCYSTEINE DL-FORM THIOLACTONE HYDROCHLORIDE, HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE [WHO-DD], HOMOCYSTEINE DL-FORM THIOLACTONE HYDROCHLORIDE [MI], 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE (1:1), homocysteine thiolactone hydrochloride, HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE, (+-)-, 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE, (+-)-, 227-923-3, 3-Aminodihydrothiophen-2(3H)-one hydrochloride, DL-Homocysteinethiolactone Hydrochloride, 3-aminothiolan-2-one hydrochloride, DL-HOMOCYSTEINETHIOLACTONE HCL, MFCD00012724, 3-aminothiolan-2-one;hydrochloride, DL-Homocysteine thiolactone (hydrochloride), Dl-homocysteine thiolactone HCl, 3622-59-1, dl Homocysteine Thiolactone Hydrochloride, 6038-19-3 (HCl), C4H8ClNOS, DL-HoMocysteine Thiolactone–d4 HCl, UNII-5D8467GAGD, 1219805-31-8, SCHEMBL1119733, CHEMBL3245370, BCP24448, NSC22879, SBB004035, AKOS008966943, FH23842, GS-3012, SB44905, AC-31997, PD103003, SY038927, DB-048115, HY-101404, CS-0021300, H0646, NS00045429, NS00122853, ST50410867, 3-Aminodihydrothiophen-2(3H)-onehydrochloride, EN300-17366, 3-aminodihydro-2(3H)-thiophenone hydrochloride, F17227, 3-amino-3,4,5-trihydrothiophen-2-one, chloride, DL-3-Aminotetrahydrothiophen-2-one Hydrochloride, Q27261865, Z56922158, (+/-)-Dihydro-3-amino-2(3H)-thiophenone hydrochloride, F2190-0527, HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE, (+/-)-, DL-Homocysteine thiolactone hydrochloride, >=99.0% (AT), 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE, (+/-)-, (+/-)-3-Amino-dihydro-thiophen-2-one hydrochloride;3-Aminodihydro-2-(3H)-thiophenone hydrochloride

DL-Homocysteine thiolactone hydrochloride is widely employed in biochemical research to investigate homocysteine metabolism and its pathological implications, including atherosclerosis and Alzheimer’s disease. It serves as a precursor for studying N-homocysteinylation of proteins, a post-translational modification linked to cellular dysfunction. Researchers also use it to model oxidative stress and develop therapeutic strategies targeting hyperhomocysteinemia. Its applications extend to synthesizing homocysteine derivatives for drug discovery and diagnostic reagent development.

Safety and Hazards

GHS Hazard Statements

• H315 (37.5%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (37.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (25%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (37.5%)
• Eye Irrit. 2 (37.5%)
• STOT SE 3 (25%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.